Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.50 |
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368286 | 0.98 | CA1 (0.52) | CA1CA2CA7CA9CA12 | |
| SCHEMBL7514704 | 0.95 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11297957 | 0.95 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL7513563 | 0.95 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL14124758 | 0.91 | LTA4H (0.54) | CA1CA2CA7CA9CA12 | |
| SCHEMBL14124827 | 0.91 | ESR2 (0.54) | CA1CA2CA7CA9CA12 | |
| SCHEMBL6326434 | 0.90 | ESR2 (0.52) | CA1CA2CA7CA9CA12 | |
| Diphenylmethanol SCHEMBL10871922 | 0.80 | ACP3 (0.49) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19593607 | 0.80 | CES2 (0.31) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11859127 | 0.80 | CA1 (0.33) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650330-B2 | Process for the synthesis of aryl sulfones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-16 | — | — | US | claimed |
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-10-20 | — | — | US | claimed |
| CN-103922976-B | Asymmetry diaryl sulfone compounds and preparation method thereof | 绍兴文理学院 | 2016-08-17 | — | — | CN | claimed |
| WO-2015087352-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-06-18 | — | — | WO | claimed |
| CN-103922976-A | Asymmetric diaryl sulfone compound and preparation method thereof | UNIV SHAOXING | 2014-07-16 | — | — | CN | claimed |
| CN-120060869-A | Electrocatalytic synthesis method of aryl sulfone compound | 平顶山学院 | 2025-05-30 | — | — | CN | disclosed |
| WO-2024147009-A1 | GPR35 MODULATORS | ThirtyFiveBio Limited (GB) | 2024-07-11 | — | — | WO | disclosed |
| WO-2023137675-A1 | USE OF NICKEL/KETONE DUAL-CATALYSIS SYSTEM IN CROSS-COUPLING REACTION OF ARYL HALIDE AND SODIUM ARYLSULFINATE | 苏州大学 | 2023-07-27 | — | — | WO | disclosed |
| CN-113387855-B | Method for synthesizing disulfide compound by visible light and titanocene complex concerted catalysis | 陕西师范大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-115490621-A | Preparation method of iodobicyclo [1.1.1] pentane derivative | 浙江工业大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-115057802-B | Polysulfide compound and preparation method and application thereof | 苏州照固新材料科技有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115197108-A | Preparation method of gamma-ketosulfone compound | 南华大学 | 2022-10-18 | — | — | CN | disclosed |
| EP-0055474-B1 | THE USE OF BETA-SULFONYLACRYLIC ACID DERIVATIVES ON A DRY BLEND CONTAINING THEM OR PELLETS MADE THEREFROM IN SYNTHETIC POLYMERS | STAUFFER CHEMICAL COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4388249-A | PROTECTION OF PLASTICS AGAINST ATTACK BY MICROORGANISMS | STAUFFER CHEMICAL COMPANY (US) | 1983-06-14 | — | — | US | disclosed |
| US-4331480-A | 3-(4-METHOXYPHENYL SULFONYL) ACRYLONITRILE AND DERIVATIVES; BACTERICIDES; FUNGICIDES) ALGICIDES | STAUFFER CHEMICAL COMPANY (US) | 1982-05-25 | — | — | US | disclosed |
| US-4301278-A | BY HYDROGENATION IN THE PRESENCE OF A CATALYST | CIBA-GEIGY CORPORATION (US) | 1981-11-17 | — | — | US | disclosed |
| US-4255328-A | CEPHALOSPORINS | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-4147864-A | Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-4049718-A | Sulphones | RHONE-POULENC, S.A. (FR) | 1977-09-20 | — | — | US | disclosed |
| US-4048234-A | Sulphones | RHONE-POULENC S.A. (FR) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | ARSA, TPST2, STS | CA1 3612/4885CA2 1552/4885CA7 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.