SCHEMBL6368288

SCHEMBL6368288

CCCCCCCCCCCCc1c(O)cccc1OC(=O)c1ccccc1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.51
HSD17B10 Q99714 2/20 0.51
KDM4E B2RXH2 1/20 0.51
CNR1 P21554 7/20 0.50
CNR2 P34972 7/20 0.50
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
NAAA Q02083 1/20 0.47
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
TSHR P16473 1/20 0.44
ALOX15 P16050 1/20 0.44
BID P55957 1/20 0.44
BCL2L1 Q07817 1/20 0.44
MCL1 Q07820 1/20 0.44
BAK1 Q16611 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6367119 0.91 CNR1 (0.49) CNR1CNR2ESR1ESR2KMT2A
SCHEMBL9131944 0.86 THRA (0.55) HSD17B10KDM4ECNR1CNR2ESR1
SCHEMBL78018 0.85 THRA (0.60) ALDH1A1HPGDHSD17B10KDM4ENAAA
SCHEMBL30431680 0.85 THRA (0.60) ALDH1A1HPGDHSD17B10KDM4ENAAA
SCHEMBL2804125 0.85 THRA (0.60) ALDH1A1HPGDHSD17B10KDM4ENAAA
SCHEMBL6368294 0.85 ALOX5 (0.57) ALDH1A1HPGDHSD17B10KDM4EALOX15
Methane SCHEMBL27981233 0.84 THRA (0.59) ALDH1A1HPGDHSD17B10KDM4ENAAA
SCHEMBL16339448 0.83 CNR1 (0.54) ALDH1A1CNR1CNR2KMT2AMEN1
SCHEMBL5134439 0.82 PPARG (0.57) CNR1CNR2BIDBCL2L1MCL1
SCHEMBL10944027 0.81 LMNA (0.59) ALDH1A1HPGDHSD17B10KDM4ECNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050181957-A1 Lubricating oil additive composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2005-08-18 US disclosed
EP-1508610-A1 LUBRICATING OIL ADDITIVE COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2005-02-23 EP disclosed
US-5686398-A Additive for lubricant or fuel, lubricating oil composition or fuel composition containing it, and substituted hydroxyaromatic ester derivative IDEMITSU KOSAN CO., LTD. (JP) 1997-11-11 US disclosed