Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971534 | 0.80 | MCOLN3 (0.51) | PKMALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6430509 | 0.76 | ITGB1 (0.38) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL5170741 | 0.70 | MEN1 (0.46) | PKMALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5171066 | 0.70 | MEN1 (0.46) | PKMALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14489550 | 0.70 | ALDH1A1 (0.69) | PKMPKLRALDH1A1KMT2AMEN1 | |
| SCHEMBL31315849 | 0.69 | PKM (0.70) | PKMPKLRALDH1A1KMT2AMEN1 | |
| SCHEMBL31684030 | 0.68 | ALDH1A1 (0.67) | PKMPKLRALDH1A1KMT2AMEN1 | |
| SCHEMBL4555427 | 0.68 | ALDH1A1 (0.67) | PKMPKLRALDH1A1KMT2AMEN1 | |
| SCHEMBL28308929 | 0.68 | ALDH1A1 (0.67) | PKMPKLRALDH1A1KMT2AMEN1 | |
| SCHEMBL21540450 | 0.67 | MAPT (0.53) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903075-B1 | Heterocyclic amide compounds as cell adhesion inhibitors | MERCK & CO., INC. (US) | 2005-06-07 | — | — | US | disclosed |