Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.62 |
| ▸ | CA1 | P00915 | 5/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | CA9 | Q16790 | 5/20 | 0.62 |
| ▸ | CA4 | P22748 | 2/20 | 0.62 |
| ▸ | CA6 | P23280 | 2/20 | 0.62 |
| ▸ | CA5A | P35218 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ly-181984 SCHEMBL4612056 | 0.88 | RECQL (0.74) | CA12CA1CA2CA9CA4 | |
| SCHEMBL23141148 | 0.83 | RECQL (0.67) | CA12CA1CA2CA9CA4 | |
| SCHEMBL1928662 | 0.81 | CA12 (0.85) | CA12CA1CA2CA9CA4 | |
| SCHEMBL9486495 | 0.81 | CA12 (0.66) | CA12CA1CA2CA9CA4 | |
| SCHEMBL6243996 | 0.81 | CA12 (0.85) | CA12CA1CA2CA9CA4 | |
| SCHEMBL5197859 | 0.78 | ENPP1 (0.71) | CA12CA1CA2CA9CA4 | |
| SCHEMBL6322949 | 0.77 | CA1 (0.74) | CA12CA1CA2CA9CA4 | |
| SCHEMBL9096201 | 0.77 | ALDH1A1 (0.60) | CA12CA1CA2CA9CA4 | |
| SCHEMBL5184835 | 0.77 | IDO1 (0.61) | CA12CA1CA2CA9CA4 | |
| SCHEMBL29973557 | 0.77 | CA1 (1.00) | CA12CA1CA2CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878514-B1 | Methods for identifying agents that inhibit serum aging factors and uses and compositions thereof | PURDUE RESEARCH FOUNDATION (US) | 2005-04-12 | — | — | US | disclosed |