SCHEMBL6369153

SCHEMBL6369153

C=Cc1cnc(C)nc1C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.38
PDXK O00764 1/20 0.32
PDK2 Q15119 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28467294 0.98 PDE10A (0.38) PDE10APDXKPDK2
SCHEMBL28988161 0.77 ALDH1A1 (0.40) PDXK
SCHEMBL30326075 0.77 ALDH1A1 (0.40) PDXK
SCHEMBL22074101 0.77 PDXK (0.31) PDXK
SCHEMBL5435005 0.77 RXFP1 (0.39) PDXKLMNA
SCHEMBL16476949 0.77 PDE10A (0.35) PDE10A
SCHEMBL29953076 0.76 MEN1 (0.36) PDK2LMNA
SCHEMBL11154637 0.71 PDXK (0.36) PDE10APDXK
SCHEMBL19308504 0.71 PDE10A (0.32) PDE10APDXK
SCHEMBL18597002 0.70 PDE10A (0.31) PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907514-A Multifunctional fiber and preparation method and application thereof 北京洁尔爽高科技有限公司 2022-08-16 CN disclosed
CN-108950645-B Aluminum and aluminum alloy anodic oxidation nickel-free sealing agent 上海铝通化学科技有限公司 2020-10-23 CN disclosed
US-10562900-B2 Indazole compounds as FGFR kinase inhibitor, preparation and use thereof SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. (CN) 2020-02-18 US disclosed
CN-108950645-A A kind of aluminium and aluminium alloy anode oxide are without nickel sealer 上海铝通化学科技有限公司 2018-12-07 CN disclosed
US-20170275291-A1 INDAZOLE COMPOUNDS AS FGFR KINASE INHIBITOR, PREPARATION AND USE THEREOF SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. (CN) 2017-09-28 US disclosed
US-8168766-B2 Process of making 2-deoxy-2,2-difluoro-D-ribofuranosyl nucleosides and intermediates therefor ScnioPharm Taiwan Ltd. (TW) 2012-05-01 US disclosed
US-20100056771-A1 Process of Making 2-Deoxy-2,2-Difluoro-D-Ribofuranosyl Nucleosides and Intermediates Therefor SCINOPHARM TAIWAN LTD. (TW) 2010-03-04 US disclosed
US-7572898-B2 Process of making an alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl sulfonate and use thereof for making a beta nucleoside SCINOPHARM TAIWAN, LTD. (TW) 2009-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10562900-B2 Indazole compounds as FGFR kinase inhibitor, preparation and use thereof FGFR1, FGFR2, FGFR3 PDE10A 3668/4885PDXK 113/4885PDK2 262/4885
US-20100056771-A1 Process of Making 2-Deoxy-2,2-Difluoro-D-Ribofuranosyl Nucleosides and Intermediates Therefor SAMHD1, DPYD, GARS1 PDE10A 4478/4885PDXK 2980/4885PDK2 1024/4885
US-20170275291-A1 INDAZOLE COMPOUNDS AS FGFR KINASE INHIBITOR, PREPARATION AND USE THEREOF FGFR1, FGFR2, FGFR3 PDE10A 3668/4885PDXK 113/4885PDK2 262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.