Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276719 | 0.89 | CRHBP (0.44) | MAPTMAPK1TDP1SMN1; SMN2CRHBP | |
| SCHEMBL7276715 | 0.89 | CRHBP (0.44) | MAPTMAPK1TDP1SMN1; SMN2CRHBP | |
| SCHEMBL7371470 | 0.88 | CRHBP (0.41) | MAPTMAPK1TDP1SMN1; SMN2CRHBP | |
| Water SCHEMBL10716192 | 0.88 | CRHBP (0.43) | MAPTMAPK1TDP1SMN1; SMN2CRHBP | |
| Hydrochloric Acid SCHEMBL6371205 | 0.88 | CRHBP (0.43) | MAPTMAPK1TDP1SMN1; SMN2CRHBP | |
| SCHEMBL26934247 | 0.82 | MMP2 (0.43) | MAPTMAPK1TDP1CRHBPCRHR2 | |
| SCHEMBL11095621 | 0.81 | MMP2 (0.41) | MAPTMAPK1TDP1SMN1; SMN2CRHBP | |
| SCHEMBL11095963 | 0.80 | MAPT (0.39) | MAPTMAPK1TDP1SMN1; SMN2CRHBP | |
| SCHEMBL3584166 | 0.79 | CRHBP (0.51) | MAPTMAPK1TDP1SMN1; SMN2CRHBP | |
| SCHEMBL7371471 | 0.78 | MAPT (0.39) | MAPTMAPK1TDP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050245432-A1 | N-methyl amino acids | UBIQUITOUS TECHNOLOGIES PTY. LTD. (AU) | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245432-A1 | N-methyl amino acids | VIP, NPPA, PTMS | MAPT 2745/4885MAPK1 1305/4885TDP1 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.