Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | HMGCR | P04035 | 4/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370942 | 0.82 | CA2 (0.52) | CA2CA1HMGCRHPNMAPT | |
| SCHEMBL5862960 | 0.80 | CA2 (0.57) | CA2CA1HMGCRHPNMAPT | |
| SCHEMBL11308547 | 0.80 | CA2 (0.57) | CA2CA1HMGCRHPNMAPT | |
| SCHEMBL7935612 | 0.78 | CA2 (0.55) | CA2CA1HMGCRHPNMAPT | |
| SCHEMBL4338446 | 0.78 | CA2 (0.59) | CA2CA1HMGCRHPNMAPT | |
| SCHEMBL5659745 | 0.76 | CA2 (0.49) | CA2CA1HMGCRHPNMAPT | |
| SCHEMBL5659743 | 0.73 | CA2 (0.53) | CA2CA1HMGCRHPNMAPT | |
| SCHEMBL28453633 | 0.72 | CA2 (0.52) | CA2CA1HMGCRHPNMAPT | |
| SCHEMBL3997816 | 0.72 | CA2 (0.47) | CA2CA1HMGCRHPNMAPT | |
| SCHEMBL5082754 | 0.71 | CA2 (0.71) | CA2CA1HPNMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124586-A1 | Alpha-substituted arylalkyl phosphonate derivatives | ILEX PRODUCTS, INC. | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124586-A1 | Alpha-substituted arylalkyl phosphonate derivatives | APOB, APOL1, LDLR | CA2 4828/4885CA1 4859/4885HMGCR 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.