Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | PTGFR | P43088 | 2/20 | 0.38 |
| ▸ | FNTA | P49354 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917463 | 0.88 | ATM (0.41) | ATMGABBR2GABBR1LMNATSHR | |
| SCHEMBL2231575 | 0.80 | GABBR2 (0.48) | ATMGABBR2GABBR1LMNATSHR | |
| SCHEMBL2230586 | 0.79 | GABBR2 (0.47) | ATMGABBR2GABBR1LMNATSHR | |
| SCHEMBL916225 | 0.78 | ATM (0.42) | ATMGABBR2GABBR1LMNATSHR | |
| SCHEMBL2231634 | 0.77 | GABBR2 (0.51) | ATMGABBR2GABBR1LMNATSHR | |
| SCHEMBL916411 | 0.76 | LMNA (0.39) | LMNATSHRCYP2C9CYP3A4CYP2C19 | |
| SCHEMBL2230117 | 0.74 | GABBR2 (0.49) | ATMGABBR2GABBR1LMNATSHR | |
| SCHEMBL8147447 | 0.74 | GABBR2 (0.49) | ATMGABBR2GABBR1LMNATSHR | |
| SCHEMBL2231735 | 0.74 | GABBR2 (0.49) | ATMGABBR2GABBR1LMNATSHR | |
| SCHEMBL19065277 | 0.74 | GABBR2 (0.43) | ATMGABBR2GABBR1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660440-B1 | ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE | XENOPORT INC (US) | 2012-02-22 | — | — | EP | disclosed |