SCHEMBL637403

SCHEMBL637403

CC(C)(C)C(C(=O)OOc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 1/20 0.39
CES1 P23141 1/20 0.39
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
ALDH1A1 P00352 2/20 0.37
ALOX15 P16050 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1960388 0.80 ELANE (0.49) KCNN4L3MBTL1ATMKMT2AALDH1A1
SCHEMBL27275827 0.77 L3MBTL1 (0.42) KCNN4L3MBTL1ATMMAPTKMT2A
Water SCHEMBL28352540 0.75 L3MBTL1 (0.38) KCNN4L3MBTL1ATMMAPTKMT2A
SCHEMBL644718 0.74 RIPK1 (0.44) L3MBTL1ATMCYP2C19ALDH1A1ALOX15
SCHEMBL14354433 0.73 MAPT (0.50) KCNN4MAPTKMT2ACES1CYP2C19
SCHEMBL18650576 0.72 CES1 (0.53) KCNN4L3MBTL1MAPTKMT2ACES1
SCHEMBL13727895 0.71 L3MBTL1 (0.38) KCNN4L3MBTL1ATMMAPTKMT2A
SCHEMBL14506460 0.70 ELANE (0.47) MAPTCYP2C19ALDH1A1ELANE
SCHEMBL6016877 0.70 MAPT (0.63) KCNN4MAPTKMT2ACYP2C19HIF1A
SCHEMBL6243239 0.69 KCNN4 (0.50) KCNN4MAPTKMT2ACES1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115145129-A Method for producing toner 佳能株式会社 2022-10-04 CN disclosed
CN-108873638-B Method for producing toner 佳能株式会社 2022-09-30 CN disclosed
CN-105278271-B Electrostatic image developing carrier, electrostatic image developer, developer cartridge, process cartridge, and image forming apparatus 富士施乐株式会社 2020-01-07 CN disclosed
US-10421828-B2 Resin composition for solid polymer fuel cell sealing material and solid polymer fuel cell sealing material using said resin composition PANAC CO., LTD. (JP) 2019-09-24 US disclosed
US-10310396-B2 Method of producing toner CANON KABUSHIKI KAISHA (JP) 2019-06-04 US disclosed
US-20180329322-A1 METHOD OF PRODUCING TONER CANON KABUSHIKI KAISHA (JP) 2018-11-15 US disclosed
CN-103324051-B Toner, developer, toner cartridge, developer box, handle box, image forming apparatus and image forming method 富士施乐株式会社 2018-06-26 CN disclosed
US-20170335026-A1 RESIN COMPOSITION FOR SOLID POLYMER FUEL CELL SEALING MATERIAL AND SOLID POLYMER FUEL CELL SEALING MATERIAL USING SAID RESIN COMPOSITION PANAC CO., LTD. (JP) 2017-11-23 US disclosed
US-8288493-B2 (meth)acrylic-modified siloxane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-10-16 US disclosed
EP-2112189-B1 (Meth)acrylic-modified siloxane compounds SHINETSU CHEMICAL CO (JP) 2012-02-22 EP disclosed
US-20090270529-A1 (METH)ACRYLIC-MODIFIED SILOXANE COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-10-29 US disclosed
EP-2112189-A1 (Meth)acrylic-modified siloxane compounds Shin-Etsu Chemical Co., Ltd. (JP) 2009-10-28 EP disclosed
US-7364826-B2 Electrostatic latent image developing toner, and method for manufacturing electrostatic latent image developer and electrostatic latent image developing toner FUJI XEROX CO., LTD. (JP) 2008-04-29 US disclosed
US-20050181295-A1 Electrostatic latent image developing toner, and method for manufacturing electrostatic latent image developer and electrostatic latent image developing toner FUJI XEROX CO., LTD. (JP) 2005-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270529-A1 (METH)ACRYLIC-MODIFIED SILOXANE COMPOUNDS MMAB, MGMT, PAM KCNN4 4380/4885L3MBTL1 372/4885ATM 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.