SCHEMBL6374341

SCHEMBL6374341

Cc1ccc(N(c2ccc(C)cc2)c2ccc3c(c2)C2(c4ccccc4-c4ccccc42)c2cc(N(c4ccc(-c5ccccc5)cc4)c4ccc(-c5ccccc5)cc4)ccc2-3)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 10/20 0.45
HPRT1 P00492 1/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
AGTR1 P30556 1/20 0.33
FLT3 P36888 1/20 0.33
PTPRC P08575 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.32
NTSR1 P30989 1/20 0.32
RAB9A P51151 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17998534 1.00 PDK2 (0.45) PDK2HPRT1ESR1ESR2MEN1
SCHEMBL14183688 1.00 PDK2 (0.45) PDK2HPRT1ESR1ESR2MEN1
SCHEMBL16366516 0.97 PDK2 (0.49) PDK2MEN1KMT2AAGTR1KDM4E
SCHEMBL18910342 0.97 PDK2 (0.45) PDK2HPRT1ESR1ESR2PTPRC
SCHEMBL19269567 0.97 PDK2 (0.47) PDK2ESR1ESR2MEN1KMT2A
SCHEMBL14597177 0.97 PDK2 (0.47) PDK2ESR1ESR2MEN1KMT2A
SCHEMBL21416415 0.94 PDK2 (0.40) PDK2HPRT1ESR1ESR2MEN1
SCHEMBL19998918 0.94 PDK2 (0.45) PDK2HPRT1ESR1ESR2MEN1
SCHEMBL16852534 0.94 PDK2 (0.40) PDK2HPRT1ESR1ESR2MEN1
SCHEMBL16996428 0.93 PDK2 (0.42) PDK2HPRT1ESR1ESR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9054319-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 US disclosed
US-9054319-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 US disclosed
US-8759819-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-06-24 US disclosed
US-8759819-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-06-24 US disclosed
US-20140131680-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-05-15 US disclosed
US-8710493-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2014-04-29 US disclosed
US-8710493-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2014-04-29 US disclosed
US-20120199817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2012-08-09 US disclosed
US-20120199817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2012-08-09 US disclosed
US-20120119197-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 US disclosed
US-20120119197-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 US disclosed
US-8106391-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-01-31 US disclosed
US-8106391-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-01-31 US disclosed
US-20100283043-A1 ORGANIC EL ELEMENT IDEMITSU LOSAN CO., LTD. 2010-11-11 US disclosed
US-20100283043-A1 ORGANIC EL ELEMENT IDEMITSU LOSAN CO., LTD. 2010-11-11 US disclosed
US-20100219404-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-09-02 US disclosed
US-20100219404-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120199817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FTO, EML4, SLC43A1 PDK2 716/4885HPRT1 85/4885ESR1 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.