⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636830 | 0.76 | ALDH1A1 (0.34) | — | |
| SCHEMBL3560704 | 0.74 | — | — | |
| SCHEMBL13548741 | 0.74 | — | — | |
| SCHEMBL546304 | 0.72 | PTK2 (0.59) | — | |
| SCHEMBL1981268 | 0.71 | ALDH1A1 (0.45) | — | |
| SCHEMBL6508526 | 0.70 | PTK2 (0.40) | — | |
| SCHEMBL652180 | 0.70 | — | — | |
| SCHEMBL7824635 | 0.69 | PTPN2 (0.58) | — | |
| SCHEMBL2948837 | 0.68 | PTPN2 (0.43) | — | |
| SCHEMBL6509499 | 0.66 | PTK2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113856495-A | Asymmetric polyether sulfone filter membrane for virus removal and preparation method thereof | 杭州科百特过滤器材有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-108658999-B | Synthesis method of 2-phenyl heterocyclic [2,3-d ] pyrimidine-4 (3H) -ketone compound | 温州大学 | 2021-02-05 | — | — | CN | claimed |
| CN-108358949-A | The preparation method of 2,4- of one kind dichloro-thiophenes simultaneously [3,2-D] pyrimidine | 南京法恩化学有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-119798275-A | Preparation method of 2, 4-dichloro-thieno [3,2, d ] pyrimidine | 安徽尖峰北卡药业有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-117820337-A | Preparation method of 12H-benzo [4,5] thiazolo [2,3-b ] quinazoline 12-ketone compound | 赣南师范大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-116272448-A | High-flux high-interception asymmetric polyethersulfone ultrafiltration membrane and preparation method thereof | 浙江泰林生命科学有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-113122245-B | Fluorescent carbon dot with narrow fluorescence emission peak half-peak width and preparation method thereof | 中国科学院理化技术研究所 | 2023-02-17 | — | — | CN | disclosed |
| CN-113856495-A | Asymmetric polyether sulfone filter membrane for virus removal and preparation method thereof | 杭州科百特过滤器材有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-113122245-A | Fluorescent carbon dot with narrow fluorescence emission peak half-peak width and preparation method thereof | 中国科学院理化技术研究所 | 2021-07-16 | — | — | CN | disclosed |
| CN-110167926-A | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS | 米托布里奇公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-108658999-A | The synthetic method of 2- phenyl heterocycles simultaneously [2,3-d] pyrimidine -4 (3H) -one class compound | 温州大学 | 2018-10-16 | — | — | CN | disclosed |
| US-20050192320-A1 | (2-Carboxamido)(3-amino)thiophene compounds | CREW ANDREW P (US) | 2005-09-01 | — | — | US | disclosed |
| US-20050154014-A1 | (2-carboxamido)(3-amino) thiophene compounds | OSI PHARMACEUTICALS, INC. | 2005-07-14 | — | — | US | disclosed |
| US-20050154014-A1 | (2-carboxamido)(3-amino) thiophene compounds | OSI PHARMACEUTICALS, INC. | 2005-07-14 | — | — | US | disclosed |
| US-20040186124-A1 | (2-carboxamido)(3-amino)thiophene compounds | OSI PHARMACEUTICALS, INC. | 2004-09-23 | — | — | US | disclosed |
| US-20040186124-A1 | (2-carboxamido)(3-amino)thiophene compounds | OSI PHARMACEUTICALS, INC. | 2004-09-23 | — | — | US | disclosed |
| WO-2004063330-A2 | (2-CARBOXAMIDO) (3-AMINO) THIOPHENE COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2004-07-29 | — | — | WO | disclosed |
| EP-0071227-B1 | ANTI-LEUKEMIC BETA-GLYCOSYL C-NUCLEOSIDES | Sloan-Kettering Institute For Cancer Research (US) | 1987-11-11 | — | — | EP | disclosed |
| US-4584369-A | ANTICANCER AGENTS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0071227-A1 | Anti-leukemic beta-glycosyl C-nucleosides | Sloan-Kettering Institute For Cancer Research (US) | 1983-02-09 | — | — | EP | disclosed |