Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.58 |
| ▸ | PTPRB | P23467 | 1/20 | 0.58 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546304 | 0.83 | PTK2 (0.59) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL13764835 | 0.76 | PTPN2 (0.72) | PTPN2PTPRBPTPN6ABCC1ACLY | |
| SCHEMBL3576557 | 0.76 | PTPN2 (0.61) | PTPN2PTPRBPTPN6ABCC1ACLY | |
| SCHEMBL12756123 | 0.76 | PTPN2 (0.61) | PTPN2PTPRBPTPN6ABCC1ACLY | |
| SCHEMBL6643211 | 0.75 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL5836577 | 0.73 | PTPN2 (1.00) | PTPN2PTPRBPTPN6ABCC1ACLY | |
| SCHEMBL5550829 | 0.73 | PTPN2 (0.68) | PTPN2PTPRBPTPN6ABCC1HCAR2 | |
| SCHEMBL1704195 | 0.73 | PTK2 (0.71) | PTPN2PTPRBPTPN6ABCC1ACLY | |
| SCHEMBL1992502 | 0.73 | CYP3A4 (0.51) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10743903 | 0.72 | PTPN2 (0.44) | PTPN2PTPRBPTPN6ABCC1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346861-B1 | THIOPHENE CONTAINING ANALOGUES OF FLUCONAZOLE AS ANTIFUNGAL AGENTS AND PROCESS THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-01-23 | — | — | EP | claimed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4658040-A | Process for manufacturing heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-14 | — | — | US | disclosed |
| US-4108867-A | 2-Aminothiophenes | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-22 | — | — | US | disclosed |