SCHEMBL6375709

SCHEMBL6375709

CCCCCCCCCCCCCCC[N+](C)(C)CC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 11/20 1.00
HTT P42858 2/20 1.00
KMT2A Q03164 1/20 1.00
HSP90AA1 P07900 2/20 0.94
RAD52 P43351 2/20 0.94
PLA2G1B P04054 1/20 0.61
ATG4B Q9Y4P1 1/20 0.61
SLC22A1 O15245 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL372738 1.00 DNM1 (1.00) DNM1HTTKMT2AHSP90AA1RAD52
SCHEMBL15965174 1.00 DNM1 (1.00) DNM1HTTKMT2AHSP90AA1RAD52
SCHEMBL8381473 1.00 DNM1 (1.00) DNM1HTTKMT2AHSP90AA1RAD52
SCHEMBL8386909 1.00 DNM1 (1.00) DNM1HTTKMT2AHSP90AA1RAD52
SCHEMBL1172093 1.00 DNM1 (1.00) DNM1HTTKMT2AHSP90AA1RAD52
SCHEMBL8383501 1.00 DNM1 (1.00) DNM1HTTKMT2AHSP90AA1RAD52
SCHEMBL668301 1.00 DNM1 (1.00) DNM1HTTKMT2AHSP90AA1RAD52
SCHEMBL1171874 1.00 DNM1 (1.00) DNM1HTTKMT2AHSP90AA1RAD52
SCHEMBL8386779 1.00 DNM1 (1.00) DNM1HTTKMT2AHSP90AA1RAD52
SCHEMBL37593 1.00 DNM1 (1.00) DNM1HTTKMT2AHSP90AA1RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005094806-A1 USE OF QUATERNARY AMMONIUM COMPOUNDS AS SPECIFIC BLOCKERS OF TRANSPORT THROUGH AQUAPORIN, COMPOSITIONS COMPRISING THE COMPOUNDS AND METHOD OF SELECTING THE COMPOUNDS STICHTING KATHOLIEKE UNIVERSITEIT (NL) 2005-10-13 WO claimed
EP-0707489-A4 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS INC (US) 1998-07-29 EP claimed
EP-0707489-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF Scotgen Biopharmaceuticals, Inc. (US) 1996-04-24 EP claimed
WO-1994025053-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS, INC. (US) 1994-11-10 WO claimed
US-11914295-B2 Thermosetting iodine- and silicon-containing material, composition containing the material for forming resist underlayer film for EUV lithography, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-02-27 US disclosed
US-20230333472-A1 THERMOSETTING IODINE- AND SILICON-CONTAINING MATERIAL, COMPOSITION CONTAINING THE MATERIAL FOR FORMING RESIST UNDERLAYER FILM FOR EUV LITHOGRAPHY, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-19 US disclosed
US-20230244149-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-03 US disclosed
US-9315670-B2 Composition for forming resist underlayer film and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-04-19 US disclosed
US-20140235796-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-08-21 US disclosed
WO-2005094806-A1 USE OF QUATERNARY AMMONIUM COMPOUNDS AS SPECIFIC BLOCKERS OF TRANSPORT THROUGH AQUAPORIN, COMPOSITIONS COMPRISING THE COMPOUNDS AND METHOD OF SELECTING THE COMPOUNDS STICHTING KATHOLIEKE UNIVERSITEIT (NL) 2005-10-13 WO disclosed
US-5955584-A NON-PROTEIN ANTIGEN COMPOSED OF STEROID COMPONENT WITH 3 BETA HYDROXY OR 3 KETO GROUP AND QUATERNARY AMMONIUM SALT; FOR THERAPY AND IMMUNOASSAY DIAGNOSIS CHARTER VENTURES (US) 1999-09-21 US disclosed
US-5811248-A Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof CHARTER VENTURES (US) 1998-09-22 US disclosed
EP-0707489-A4 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS INC (US) 1998-07-29 EP disclosed
EP-0707489-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF Scotgen Biopharmaceuticals, Inc. (US) 1996-04-24 EP disclosed
WO-1994025053-A1 ATHEROSCLEROTIC PLAQUE SPECIFIC ANTIGENS, ANTIBODIES THERETO, AND USES THEREOF SCOTGEN BIOPHARMACEUTICALS, INC. (US) 1994-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230333472-A1 THERMOSETTING IODINE- AND SILICON-CONTAINING MATERIAL, COMPOSITION CONTAINING THE MATERIAL FOR FORMING RESIST UNDERLAYER FILM FOR EUV LITHOGRAPHY, AND PATTERNING PROCESS RPS4X, SIK3, MLX DNM1 4060/4885HTT 2857/4885KMT2A 1118/4885
US-11914295-B2 Thermosetting iodine- and silicon-containing material, composition containing the material for forming resist underlayer film for EUV lithography, and patterning process RPS4X, SIK3, MLX DNM1 4060/4885HTT 2857/4885KMT2A 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.