Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719073 | 0.87 | PDCD1 (0.30) | PDCD1CD274 | |
| SCHEMBL5345743 | 0.78 | HTR1A (0.34) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL8151555 | 0.77 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL7602972 | 0.77 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL5354721 | 0.77 | HTR1A (0.33) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL5067415 | 0.77 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL7597783 | 0.75 | — | — | |
| SCHEMBL5352543 | 0.74 | — | — | |
| SCHEMBL6893245 | 0.69 | HTR1A (0.31) | — | |
| SCHEMBL6065652 | 0.68 | EDNRB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |