Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598786 | 0.82 | HTR1A (0.30) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL797644 | 0.81 | GCGR (0.34) | PDCD1CD274 | |
| SCHEMBL7597779 | 0.80 | IDO1 (0.33) | ALDH1A1 | |
| SCHEMBL5345743 | 0.78 | HTR1A (0.34) | PDCD1CD274HTR1AHTR7HTR2B | |
| SCHEMBL5067415 | 0.77 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| SCHEMBL7599191 | 0.77 | HTR1A (0.34) | PDCD1CD274HTR1AHTR7HTR2B | |
| SCHEMBL6375930 | 0.77 | PDCD1 (0.31) | PDCD1CD274CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL5616347 | 0.77 | PDCD1 (0.34) | PDCD1CD274HTR1AHTR7HTR2B | |
| SCHEMBL5354721 | 0.77 | HTR1A (0.33) | PDCD1CD274HTR1AHTR7BRD4 | |
| SCHEMBL7597783 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |