Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.58 |
| ▸ | NOS1 | P29475 | 1/20 | 0.58 |
| ▸ | NOS2 | P35228 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.55 |
| ▸ | RELA | Q04206 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833507 | 0.87 | SMN1; SMN2 (0.62) | NOS3NOS1NOS2RAB9ANPC1 | |
| SCHEMBL1268987 | 0.84 | RAB9A (0.64) | NOS3NOS1NOS2RAB9ANPC1 | |
| SCHEMBL9835001 | 0.84 | RAB9A (0.59) | NOS3NOS1NOS2RAB9ANPC1 | |
| SCHEMBL7814469 | 0.83 | NOS3 (0.53) | NOS3NOS1NOS2RAB9ANPC1 | |
| SCHEMBL9276001 | 0.82 | RAB9A (0.62) | NOS3NOS1NOS2RAB9ANPC1 | |
| SCHEMBL9274369 | 0.82 | NOS3 (0.54) | NOS3NOS1NOS2RAB9ANPC1 | |
| SCHEMBL9834816 | 0.82 | RAB9A (0.58) | NOS3NOS1NOS2RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7818020 | 0.82 | NOS3 (0.52) | NOS3NOS1NOS2RAB9ANPC1 | |
| SCHEMBL8305285 | 0.81 | NOS3 (0.51) | NOS3NOS1NOS2RAB9ANPC1 | |
| SCHEMBL9836498 | 0.81 | RAB9A (0.78) | NOS3NOS1NOS2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884810-B2 | Benzimidazole derivatives | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1428825-A1 | BENZIMIDAZOLE DERIVATIVES | Zeria Pharmaceutical Co., Ltd. (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-20030236411-A1 | Benzimidazole derivatives | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236411-A1 | Benzimidazole derivatives | CYP2E1, CYP1A1, CYP1B1 | NOS3 649/4885NOS1 325/4885NOS2 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.