Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.54 |
| ▸ | CA2 | P00918 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637737 | 0.84 | GAA (0.52) | CA1CA2ALDH1A1MAPTKDM4E | |
| SCHEMBL13306472 | 0.80 | CA12 (0.63) | CA1CA2ALDH1A1MAPTKMT2A | |
| SCHEMBL4121702 | 0.77 | OPRK1 (0.62) | ALDH1A1MAPTKDM4EGLAHPGD | |
| SCHEMBL10329430 | 0.77 | OPRK1 (0.62) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL27698153 | 0.77 | ALDH1A1 (0.53) | CA1CA2ALDH1A1MAPTKDM4E | |
| SCHEMBL12657551 | 0.77 | KMT2A (0.45) | ALDH1A1MAPTKMT2AMEN1OPRK1 | |
| SCHEMBL27474162 | 0.77 | PPARG (0.56) | ALDH1A1MAPTKDM4EGLAGAA | |
| SCHEMBL580319 | 0.77 | NAMPT (0.57) | CA1CA2ALDH1A1MAPTGLA | |
| SCHEMBL11284305 | 0.76 | OPRK1 (0.61) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL8223629 | 0.76 | KMT2A (0.60) | CA1CA2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222296-B2 | Conjugates comprising a GABA- or glycine compound, pharmaceutical compositions and combinations thereof and their use in treating CNS disorders | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-07-17 | — | — | US | disclosed |
| US-20090304584-A1 | CONJUGATES COMPRISING A GABA- OR GLYCINE COMPOUND, PHARMACEUTICAL COMPOSITIONS AND COMBINATIONS THEREOF AND THEIR USE IN TREATING CNS DISORDERS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090304584-A1 | CONJUGATES COMPRISING A GABA- OR GLYCINE COMPOUND, PHARMACEUTICAL COMPOSITIONS AND COMBINATIONS THEREOF AND THEIR USE IN TREATING CNS DISORDERS | GABBR1, GABBR2, GABRG3 | CA1 662/4885CA2 1637/4885ALDH1A1 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.