Phosphoric Acid

Phosphoric Acid

SCHEMBL637835

CCNc1ccccc1[N+](=O)[O-].O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O

nearest known ligand 0.54

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.53
MEN1 O00255 2/20 0.53
KAT2B Q92831 2/20 0.53
HCAR3 P49019 1/20 0.52
TP53 P04637 1/20 0.51
MAPT P10636 6/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
MAPK1 P28482 2/20 0.50
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
GAA P10253 1/20 0.49
CASP7 P55210 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HTT P42858 1/20 0.47
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162875 0.92 KAT2B (0.60) KMT2AMEN1KAT2BHCAR3TP53
Hydrochloric Acid SCHEMBL3652036 0.90 KAT2B (0.61) KMT2AMEN1KAT2BHCAR3TP53
Bromide SCHEMBL28202540 0.90 KAT2B (0.58) KMT2AMEN1KAT2BHCAR3TP53
Phosphoric Acid SCHEMBL28639142 0.80 GPR35 (0.56) KMT2AMEN1MAPTALDH1A1NPC1
SCHEMBL4077151 0.78 KAT2B (0.66) KMT2AMEN1KAT2BHCAR3TP53
Phosphoric Acid SCHEMBL20984352 0.78 KMT2A (0.53) KMT2AMEN1KAT2BTP53MAPT
SCHEMBL9781715 0.77 KAT2B (0.64) KMT2AMEN1KAT2BMAPTL3MBTL1
SCHEMBL29516821 0.77 KAT2B (0.64) KMT2AMEN1KAT2BMAPTL3MBTL1
SCHEMBL6198859 0.77 KAT2B (0.80) KMT2AMEN1KAT2BMAPTL3MBTL1
SCHEMBL3160883 0.76 MEN1 (0.54) KMT2AMEN1KAT2BMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8119364-B2 Methods for generating analogs of coenzyme A THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-02-21 US disclosed
US-20100304430-A1 Methods for Generating Analogs of Coenzyme A THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-12-02 US disclosed
US-7727738-B2 Methods for generating analogs of coenzyme A THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-06-01 US disclosed
US-20070128683-A1 Metabolic delivery of coenzyme A analogs NATIONAL SCIENCE FOUNDATION 2007-06-07 US disclosed