Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL28789392 | 0.87 | GPR35 (0.64) | GPR35ALDH1A1HSD17B10TDP1MEN1 | |
| Nitrophenolate SCHEMBL158596 | 0.87 | GPR35 (0.57) | GPR35ALDH1A1HSD17B10TDP1CTSD | |
| Nitrophenolate SCHEMBL8469921 | 0.87 | GPR35 (0.57) | GPR35ALDH1A1HSD17B10TDP1CTSD | |
| SCHEMBL29577518 | 0.87 | HSD17B10 (0.67) | GPR35ALDH1A1HSD17B10TDP1MEN1 | |
| SCHEMBL22566 | 0.87 | HSD17B10 (0.67) | GPR35ALDH1A1HSD17B10TDP1MEN1 | |
| SCHEMBL16355165 | 0.87 | HSD17B10 (0.67) | GPR35ALDH1A1HSD17B10TDP1MEN1 | |
| Ammonia Solution, Strong SCHEMBL27641539 | 0.84 | HSD17B10 (0.58) | GPR35ALDH1A1HSD17B10TDP1MEN1 | |
| Nitric Acid SCHEMBL27633028 | 0.84 | GPR35 (0.61) | GPR35ALDH1A1HSD17B10TDP1CTSD | |
| Methyl Alcohol SCHEMBL27808930 | 0.84 | HSD17B10 (0.65) | GPR35ALDH1A1HSD17B10TDP1MEN1 | |
| Fluoride SCHEMBL11797732 | 0.84 | HSD17B10 (0.64) | GPR35ALDH1A1HSD17B10TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113583152-B | Cyclodextrin-europium molybdate/lanthanum hybrid microsphere, preparation method thereof and application thereof in fluorescent detection of phosphorus-containing compound | 同济大学 | 2022-07-05 | — | — | CN | claimed |
| CN-113583152-A | Cyclodextrin-europium molybdate/lanthanum hybrid microsphere, preparation method thereof and application thereof in fluorescent detection of phosphorus-containing compound | 同济大学 | 2021-11-02 | — | — | CN | claimed |
| CN-113583152-B | Cyclodextrin-europium molybdate/lanthanum hybrid microsphere, preparation method thereof and application thereof in fluorescent detection of phosphorus-containing compound | 同济大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-113583152-B | Cyclodextrin-europium molybdate/lanthanum hybrid microsphere, preparation method thereof and application thereof in fluorescent detection of phosphorus-containing compound | 同济大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-113583152-A | Cyclodextrin-europium molybdate/lanthanum hybrid microsphere, preparation method thereof and application thereof in fluorescent detection of phosphorus-containing compound | 同济大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-113583152-A | Cyclodextrin-europium molybdate/lanthanum hybrid microsphere, preparation method thereof and application thereof in fluorescent detection of phosphorus-containing compound | 同济大学 | 2021-11-02 | — | — | CN | disclosed |