Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 6/20 | 0.38 |
| ▸ | NOS1 | P29475 | 6/20 | 0.38 |
| ▸ | NOS2 | P35228 | 6/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892843 | 1.00 | LMNA (0.40) | LMNANOS3NOS1NOS2CYP2D6 | |
| SCHEMBL10892852 | 1.00 | LMNA (0.40) | LMNANOS3NOS1NOS2CYP2D6 | |
| SCHEMBL10895234 | 1.00 | LMNA (0.40) | LMNANOS3NOS1NOS2CYP2D6 | |
| SCHEMBL5864938 | 0.98 | — | — | |
| SCHEMBL932427 | 0.91 | — | — | |
| SCHEMBL6379615 | 0.83 | CYP2D6 (0.40) | LMNANOS3NOS1NOS2CYP2D6 | |
| SCHEMBL9639069 | 0.78 | NOS3 (0.38) | LMNANOS3NOS1NOS2CYP2D6 | |
| SCHEMBL5865174 | 0.75 | NOS3 (0.42) | LMNANOS3NOS1NOS2CYP2D6 | |
| SCHEMBL2382858 | 0.75 | NOS3 (0.42) | LMNANOS3NOS1NOS2CYP2D6 | |
| SCHEMBL5098524 | 0.75 | NOS3 (0.42) | LMNANOS3NOS1NOS2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395726-B1 | REDUCTION OF CARBOXYL END GROUPS IN POLYESTER WITH LACTIM ETHERS | AlliedSignal Inc. (US) | 1992-07-15 | — | — | EP | claimed |
| US-11053206-B2 | Hydrofluorocarboximidate and methods of making and using the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-07-06 | — | — | US | disclosed |
| US-20200207727-A1 | HYDROFLUOROCARBOXIMIDATE AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2020-07-02 | — | — | US | disclosed |
| EP-1076054-B1 | PROCESS FOR PRODUCING ε-CAPROLACTAME | SUMITOMO CHEMICAL CO (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-6344557-B1 | REARRANGEMENT FROM 1-AZA-2-ALKOXY-1-CYCLOHEPTENE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-02-05 | — | — | US | disclosed |
| EP-1076054-A1 | PROCESS FOR PRODUCING $g(e)-CAPROLACTAM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-14 | — | — | EP | disclosed |
| EP-0395726-B1 | REDUCTION OF CARBOXYL END GROUPS IN POLYESTER WITH LACTIM ETHERS | AlliedSignal Inc. (US) | 1992-07-15 | — | — | EP | disclosed |
| EP-0395726-A1 | REDUCTION OF CARBOXYL END GROUPS IN POLYESTER WITH LACTIM ETHERS. | ALLIED SIGNAL INC (US) | 1990-11-07 | — | — | EP | disclosed |
| WO-1989008160-A1 | REDUCTION OF CARBOXYL END GROUPS IN POLYESTER WITH LACTIM ETHERS | ALLIED-SIGNAL INC. (US) | 1989-09-08 | — | — | WO | disclosed |
| US-4839124-A | Reduction of carboxyl end groups in polyester fibers with lactim ethers | ALLIED-SIGNAL INC. (US) | 1989-06-13 | — | — | US | disclosed |
| US-4469653-A | AS POLYMERIZATION CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-09-04 | — | — | US | disclosed |
| US-4404205-A | CARDIOTONIC AGENTS; ANGINA PECTORIS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-09-13 | — | — | US | disclosed |
| EP-0069295-A1 | Process for the manufacture of possibly cellular polyurethane or polyurethane-polyurea moulded articles | BASF Aktiengesellschaft (DE) | 1983-01-12 | — | — | EP | disclosed |
| US-4073783-A | PENICILLINS | PFIZER INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4052382-A | 1-PHENYL-3-AZACARBOCYCLIC-UREAS | STERLING DRUG INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4026938-A | 1-Phenyl-3-azacarbocyclic-ureas | STERLING DRUG INC. (US) | 1977-05-31 | — | — | US | disclosed |
| US-4025506-A | PENICILLINS | PFIZER INC. (US) | 1977-05-24 | — | — | US | disclosed |
| US-4025504-A | PENICILLINS | PFIZER INC. (US) | 1977-05-24 | — | — | US | disclosed |
| US-3963748-A | 1-Phenyl-3-azacarbocyclic-ureas | STERLING DRUG INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3951952-A | 6-(ALPHA-(AMIDINO-AND IMIDOYLAMINOALKANOYLAMINO)ARACYLAMINO)-PENICILLANIC ACIDS | PFIZER INC. (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053206-B2 | Hydrofluorocarboximidate and methods of making and using the same | AFF1, AFF2, RFT1 | LMNA 3798/4885NOS3 1070/4885NOS1 757/4885 |
| US-20200207727-A1 | HYDROFLUOROCARBOXIMIDATE AND METHODS OF MAKING AND USING THE SAME | AFF1, AFF2, RFT1 | LMNA 3798/4885NOS3 1070/4885NOS1 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.