⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892843 | 0.98 | LMNA (0.40) | — | |
| SCHEMBL10895234 | 0.98 | LMNA (0.40) | — | |
| SCHEMBL6379342 | 0.98 | LMNA (0.40) | — | |
| SCHEMBL10892852 | 0.98 | LMNA (0.40) | — | |
| SCHEMBL932427 | 0.93 | — | — | |
| SCHEMBL6379615 | 0.81 | CYP2D6 (0.40) | — | |
| SCHEMBL9639069 | 0.76 | NOS3 (0.38) | — | |
| SCHEMBL343554 | 0.73 | — | — | |
| SCHEMBL18989154 | 0.72 | NOS3 (0.42) | — | |
| SCHEMBL9781399 | 0.72 | NOS3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067113-A1 | HYDROFLUOROCABOXIMIDATE AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-04-04 | — | — | WO | disclosed |
| US-7030138-B2 | Benzamidine derivatives | SANKYO COMPANY, LIMITED (JP) | 2006-04-18 | — | — | US | disclosed |
| US-20040147555-A1 | Benzamidine derivatives | SANKYO COMPANY, LIMITED (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1375482-A1 | BENZAMIDINE DERIVATIVE | Sankyo Company, Limited (JP) | 2004-01-02 | — | — | EP | disclosed |
| EP-0069295-B1 | PROCESS FOR THE MANUFACTURE OF POSSIBLY CELLULAR POLYURETHANE OR POLYURETHANE-POLYUREA MOULDED ARTICLES | BASF Aktiengesellschaft (DE) | 1986-05-21 | — | — | EP | disclosed |
| US-4469653-A | AS POLYMERIZATION CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-09-04 | — | — | US | disclosed |
| US-4251542-A | Imino compounds | CIBA-GEIGY CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| US-4130652-A | 2-(Iminoethylidene)-pyrrolidines and tautomeric 2-(aminoethenyl)-1-pyrrolines | CIBA-GEIGY CORPORATION (US) | 1978-12-19 | — | — | US | disclosed |