Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 5/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.50 |
| ▸ | XDH | P47989 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222102 | 0.77 | PDPK1 (0.63) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL29711624 | 0.74 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| SCHEMBL6379588 | 0.72 | PDPK1 (0.58) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL29620672 | 0.71 | PDPK1 (0.56) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL29514836 | 0.71 | PDPK1 (0.56) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL6267288 | 0.71 | PDPK1 (0.56) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL215054 | 0.71 | PDPK1 (0.56) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL2179783 | 0.71 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL9809157 | 0.71 | PDPK1 (0.45) | PI4KAPI4K2BPI4K2API4KBXDH | |
| SCHEMBL29605437 | 0.70 | PDPK1 (0.54) | PI4KAPI4K2BPI4K2API4KBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501850-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093290-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2003-11-13 | — | — | WO | claimed |