SCHEMBL2179783

SCHEMBL2179783

NCCCCCCNc1nc2ncnc(N)c2[nH]1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PI4KA P42356 5/20 0.56
▸ PI4K2B Q8TCG2 5/20 0.56
▸ PI4K2A Q9BTU6 5/20 0.56
▸ PI4KB Q9UBF8 5/20 0.56
▸ PIM1 P11309 2/20 0.49
▸ ADORA2A P29274 1/20 0.46
▸ ADORA1 P30542 1/20 0.46
▸ NUDT1 P36639 2/20 0.43
▸ XDH P47989 3/20 0.43
▸ TSHR P16473 1/20 0.40
▸ LMNA P02545 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ APEX1 P27695 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7598522 0.84 PIM1 (0.50) PI4KAPI4K2BPI4K2API4KBPIM1
Niacinamide SCHEMBL8510810 0.81 PI4KA (0.44) PI4KAPI4K2BPI4K2API4KBPIM1
SCHEMBL29711624 0.81 PI4KA (0.59) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL16197989 0.74 XDH (0.77) XDH
SCHEMBL8920386 0.73 DHFR (0.46) PI4KAPI4K2BPI4K2API4KBLMNA
SCHEMBL8196752 0.72 XDH (0.76) XDH
SCHEMBL31045570 0.72 ADORA2A (0.44) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL14778071 0.72 PI4KA (0.62) PI4KAPI4K2BPI4K2API4KBPIM1
SCHEMBL6380386 0.71 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBADORA2A
SCHEMBL29400753 0.70 ADORA2A (0.66) PI4KAPI4K2BPI4K2API4KBADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559763-B2 FAD2 genes and mutations CIBUS US LLC (US) 2026-02-24 — — US disclosed
EP-3772905-B1 FAD2 GENES AND MUTATIONS CIBUS US LLC (US) 2026-02-18 — — EP disclosed
EP-4136963-B1 METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR CIBUS US LLC (US) 2026-01-21 — — EP disclosed
US-12331303-B2 Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair CIBUS US LLC (US) 2025-06-17 — — US disclosed
US-20250066805-A1 METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR CIBUS US LLC (US) 2025-02-27 — — US disclosed
CN-118830491-A Shatterproof genes and mutations 希博斯美国有限公司 2024-10-25 — — CN disclosed
CN-118834883-A Shatterproof genes and mutations 希博斯美国有限公司 2024-10-25 — — CN disclosed
US-20240336931-A1 SHATTERPROOF GENES AND MUTATIONS CIBUS US LLC (US) 2024-10-10 — — US disclosed
CN-111819285-B Shatterproof genes and mutations 希博斯美国有限公司 2024-08-09 — — CN disclosed
US-20240263195-A1 NON-VIRAL DELIVERY OF DNA FOR PROLONGED POLYPEPTIDE EXPRESSION IN VIVO ARES CAPITAL CORPORATION, AS AGENT 2024-08-08 — — US disclosed
US-5817786-A Single-stranded labelled oligonucleotides of preselected sequences MOLECULAR BIOSYSTEMS, INC. (US) 1998-10-06 — — US disclosed
US-5700919-A Modified phosphoramidite process for the production of modified nucleic acids BOEHRINGER MANNHIEM GMBH (DE) 1997-12-23 — — US disclosed
US-5668266-A Synthesis of single-stranded labelled oligonucleotides of preselected sequence SYNGENE, INC. (US) 1997-09-16 — — US disclosed
US-5541313-A Single-stranded labelled oligonucleotides of preselected sequence MOLECULAR BIOSYSTEMS, INC. (US) 1996-07-30 — — US disclosed
EP-0399330-B1 Modified phosphoramidite process for preparing modified nucleic acids BOEHRINGER MANNHEIM GMBH (DE) 1994-12-28 — — EP disclosed
US-4948882-A Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis SYNGENE, INC. (US) 1990-08-14 — — US disclosed
EP-0135587-B1 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS SYNGENE, INC. (US) 1990-05-02 — — EP disclosed
EP-0135587-A4 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. MOLECULAR BIOSYSTEMS INC (US) 1986-04-02 — — EP disclosed
EP-0135587-A1 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. MOLECULAR BIOSYSTEMS INC (US) 1985-04-03 — — EP disclosed
WO-1984003285-A1 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS MOLECULAR BIOSYSTEMS INC (US) 1984-08-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240263195-A1 NON-VIRAL DELIVERY OF DNA FOR PROLONGED POLYPEPTIDE EXPRESSION IN VIVO LNPEP, CD2BP2, VEGFA PI4KA 3210/4885PI4K2B 3200/4885PI4K2A 2760/4885
US-12559763-B2 FAD2 genes and mutations FADS2, FADS1, SCD PI4KA 1927/4885PI4K2B 875/4885PI4K2A 983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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