Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349126 | 0.93 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL18759326 | 0.86 | GAA (0.58) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL10874691 | 0.86 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL255251 | 0.85 | GAA (0.76) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL28212893 | 0.85 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL7211938 | 0.84 | LMNA (0.54) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL20392869 | 0.83 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL8506869 | 0.83 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL8507006 | 0.83 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL27386734 | 0.83 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143328-B | Polymer material | 嘉洛斯控股有限公司 | 2019-11-05 | — | — | CN | disclosed |
| EP-1440052-A1 | BENZAMIDE DERIVATIVES AS ANTAGONISTS OF OREXIN RECEPTORS | SMITHKLINE BEECHAM PLC (GB) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003037847-A1 | BENZAMIDE DERIVATIVES AS ANTAGONISTS OF OREXIN RECEPTORS | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-05-08 | — | — | WO | disclosed |