Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380819 | 0.86 | EPHX1 (0.67) | KMT2AEPHX1RAB9ANPC1MEN1 | |
| SCHEMBL6382778 | 0.84 | TSHR (0.62) | TSHRKMT2AEPHX1RAB9ANPC1 | |
| SCHEMBL4638157 | 0.83 | TSHR (0.51) | TSHRKMT2ARAB9ANPC1MEN1 | |
| SCHEMBL6789874 | 0.83 | EPHX1 (0.49) | KMT2AEPHX1MEN1SMN1; SMN2MAPT | |
| SCHEMBL6790368 | 0.83 | EPHX1 (0.49) | KMT2AEPHX1MEN1SMN1; SMN2MAPT | |
| SCHEMBL5726563 | 0.82 | EPHX1 (0.53) | TSHREPHX1NFKB1CNR1SLC6A3 | |
| SCHEMBL5727321 | 0.82 | EPHX1 (0.53) | TSHREPHX1NFKB1CNR1SLC6A3 | |
| SCHEMBL5727545 | 0.82 | EPHX1 (0.53) | TSHREPHX1NFKB1CNR1SLC6A3 | |
| SCHEMBL6789868 | 0.80 | EPHX1 (0.49) | KMT2AEPHX1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL6790366 | 0.80 | EPHX1 (0.49) | KMT2AEPHX1RAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250853-A1 | Beta-tubulin inhibitors | GAUDREAULT RENE C | 2005-11-10 | — | — | US | disclosed |
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| US-20020115722-A1 | SS tubulin inhibitors | SOVAR, SOCIETE EN COMMANDITE (CA) | 2002-08-22 | — | — | US | disclosed |
| US-5750547-A | Certain carbanate anti-cancer agents | UNIVERSITE LAVAL (CA) | 1998-05-12 | — | — | US | disclosed |
| US-5530026-A | WITHOUT SYSTEMIC TOXICITY AND MUTAGENICITY | UNIVERSITE LAVAL (CA) | 1996-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250853-A1 | Beta-tubulin inhibitors | TUBB, TUBB1, TUBB3 | TSHR 3261/4885KMT2A 4402/4885EPHX1 3468/4885 |
| US-20020115722-A1 | SS tubulin inhibitors | TUBB1, TUBB, TUBB3 | TSHR 2930/4885KMT2A 4264/4885EPHX1 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.