Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.67 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727321 | 0.86 | EPHX1 (0.53) | EPHX1TAS1R3TAS1R1EPHX2CNR1 | |
| SCHEMBL5726563 | 0.86 | EPHX1 (0.53) | EPHX1TAS1R3TAS1R1EPHX2CNR1 | |
| SCHEMBL5727545 | 0.86 | EPHX1 (0.53) | EPHX1TAS1R3TAS1R1EPHX2CNR1 | |
| SCHEMBL6380441 | 0.86 | TSHR (0.56) | EPHX1TAS1R3TAS1R1CNR1MEN1 | |
| SCHEMBL6790366 | 0.84 | EPHX1 (0.49) | EPHX1TAS1R3TAS1R1CNR1MEN1 | |
| SCHEMBL5767286 | 0.84 | EPHX1 (0.49) | EPHX1TAS1R3TAS1R1CNR1MEN1 | |
| SCHEMBL6789868 | 0.84 | EPHX1 (0.49) | EPHX1TAS1R3TAS1R1CNR1MEN1 | |
| SCHEMBL10939812 | 0.83 | CNR1 (0.70) | CNR1RAB9ANPC1CASRSMN1; SMN2 | |
| SCHEMBL4638759 | 0.82 | EGFR (0.47) | EPHX1TAS1R3TAS1R1EPHX2MEN1 | |
| SCHEMBL30797082 | 0.82 | MEN1 (0.54) | EPHX1MEN1KMT2ACA2CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| US-20050250853-A1 | Beta-tubulin inhibitors | GAUDREAULT RENE C | 2005-11-10 | — | — | US | disclosed |
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| US-20020115722-A1 | SS tubulin inhibitors | SOVAR, SOCIETE EN COMMANDITE (CA) | 2002-08-22 | — | — | US | disclosed |
| WO-2001047504-A2 | β-TUBELIN INHIBITORS AND THEIR USE AGAINST CANCER | UNIVERSITé LAVAL (CA) | 2001-07-05 | — | — | WO | disclosed |
| US-5530026-A | WITHOUT SYSTEMIC TOXICITY AND MUTAGENICITY | UNIVERSITE LAVAL (CA) | 1996-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250853-A1 | Beta-tubulin inhibitors | TUBB, TUBB1, TUBB3 | EPHX1 3468/4885TAS1R3 3818/4885TAS1R1 3681/4885 |
| US-20020115722-A1 | SS tubulin inhibitors | TUBB1, TUBB, TUBB3 | EPHX1 3357/4885TAS1R3 2895/4885TAS1R1 2481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.