Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6378848 | 0.76 | ADORA2A (0.36) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL17450996 | 0.76 | RAB9A (0.48) | SQORMEN1KMT2AMAPTTSHR | |
| SCHEMBL17450614 | 0.76 | MAPT (0.59) | KMT2AMAPTCYP11B1CYP11B2LTA4H | |
| SCHEMBL17633538 | 0.76 | RAB9A (0.51) | MEN1KMT2AMAPTATMCYP11B1 | |
| SCHEMBL1753086 | 0.76 | SLC5A2 (0.53) | MEN1KMT2AMAPTCYP11B1CYP11B2 | |
| SCHEMBL1752842 | 0.76 | CASP1 (0.47) | MEN1KMT2ATSHRCYP11B1CYP11B2 | |
| SCHEMBL1752806 | 0.75 | SQOR (0.53) | SQORMEN1KMT2AMAPTTSHR | |
| SCHEMBL581809 | 0.75 | SMN1; SMN2 (0.53) | SQORMEN1KMT2AMAPTTSHR | |
| SCHEMBL4062873 | 0.73 | SQOR (0.47) | SQORMEN1KMT2AMAPTTSHR | |
| SCHEMBL581362 | 0.73 | SMN1; SMN2 (0.51) | SQORMEN1KMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1217001-B1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | EISAI CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6599917-B1 | A squalene-synthesizing enzyme inhibitor, a cholesterol biosynthesis inhibitor and a triglyceride biosynthesis inhibitor | EISAI CO., LTD. (JP) | 2003-07-29 | — | — | US | disclosed |
| EP-1217001-A1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |