Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463664 | 0.88 | MAPT (0.70) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL6688407 | 0.87 | KMT2A (0.55) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL29128669 | 0.85 | MAPT (0.56) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL6688013 | 0.85 | EPHX1 (0.61) | MAPTMEN1KMT2ASMN1; SMN2EPHX1 | |
| SCHEMBL24211435 | 0.84 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL15601832 | 0.84 | MAPT (0.55) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL6690073 | 0.84 | KMT2A (0.56) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL6693475 | 0.84 | HPSE (0.59) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL6689121 | 0.84 | EPHX1 (0.63) | MEN1KMT2ASMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL6691753 | 0.84 | EPHX1 (0.63) | MEN1KMT2ASMN1; SMN2EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250853-A1 | Beta-tubulin inhibitors | GAUDREAULT RENE C | 2005-11-10 | — | — | US | disclosed |
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004106292-A1 | HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| US-20020115722-A1 | SS tubulin inhibitors | SOVAR, SOCIETE EN COMMANDITE (CA) | 2002-08-22 | — | — | US | disclosed |
| WO-2001047504-A2 | β-TUBELIN INHIBITORS AND THEIR USE AGAINST CANCER | UNIVERSITé LAVAL (CA) | 2001-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250853-A1 | Beta-tubulin inhibitors | TUBB, TUBB1, TUBB3 | MAPT 42/4885MEN1 4134/4885KMT2A 4402/4885 |
| US-20020115722-A1 | SS tubulin inhibitors | TUBB1, TUBB, TUBB3 | MAPT 47/4885MEN1 4129/4885KMT2A 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.