Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595960 | 0.86 | ALDH1A1 (0.38) | GRIA1GRIA2GRIA3GRIA4MITF | |
| SCHEMBL6375260 | 0.85 | GLP1R (0.43) | ALDH1A1 | |
| SCHEMBL6376375 | 0.85 | GLP1R (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6606958 | 0.84 | ALDH1A1 (0.36) | MITFALDH1A1SMN1; SMN2 | |
| SCHEMBL6603200 | 0.82 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4MITF | |
| SCHEMBL6601059 | 0.80 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4MITF | |
| SCHEMBL6602490 | 0.79 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4MITF | |
| SCHEMBL6604555 | 0.79 | ALDH1A1 (0.44) | MITFALDH1A1SMN1; SMN2 | |
| SCHEMBL6603316 | 0.79 | ALDH1A1 (0.45) | MITFALDH1A1SMN1; SMN2 | |
| SCHEMBL6376052 | 0.79 | ALDH1A1 (0.45) | MITFALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156047-B1 | 6-SUBSTITUTED-7- HETEROQUINOXALINE CARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-6632813-B1 | 6-subtituted-7-heteroquinoxalinecarboxylic acid derivatives and addition salts thereof and processes for the preparation of both | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-14 | — | — | US | disclosed |
| EP-1156047-A1 | 6-SUBSTITUTED-7- HETEROQUINOXALINE CARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |