Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380913 | 0.86 | GRIA1 (0.41) | ALDH1A1MITFSMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL6595978 | 0.85 | NOTUM (0.39) | ALDH1A1HPGD | |
| SCHEMBL6594520 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDMITFSMN1; SMN2GALR2 | |
| SCHEMBL6606958 | 0.73 | ALDH1A1 (0.36) | ALDH1A1HPGDMITFSMN1; SMN2GALR2 | |
| SCHEMBL1313884 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HPGDMITFSMN1; SMN2GALR2 | |
| SCHEMBL6595746 | 0.71 | NOTUM (0.38) | ALDH1A1HPGD | |
| SCHEMBL6376375 | 0.71 | GLP1R (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6603200 | 0.69 | GRIA1 (0.41) | ALDH1A1HPGDMITFSMN1; SMN2GALR2 | |
| SCHEMBL6602490 | 0.68 | GRIA1 (0.41) | ALDH1A1HPGDMITFSMN1; SMN2GALR2 | |
| SCHEMBL6600183 | 0.67 | L3MBTL1 (0.43) | ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156044-B1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6562839-B1 | Effective for the therapy of disorder of cerebral nerve cells as antagonists against excitatory amino acid receptors | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-1156044-A1 | 6-SUBSTITUTED HETEROQUINOLINECARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |