Fendiline

Fendiline

SCHEMBL63814

CC(NCCC(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 1.00
CYP3A4 P08684 2/20 1.00
LMNA P02545 2/20 1.00
HTR1A P08908 2/20 1.00
ADORA3 P0DMS8 2/20 1.00
SLC6A2 P23975 2/20 1.00
SLC6A4 P31645 2/20 1.00
ADRA1A P35348 2/20 1.00
DRD3 P35462 2/20 1.00
SLC6A3 Q01959 2/20 1.00
KCNH2 Q12809 2/20 1.00
CASR P41180 2/20 1.00
CYP1A2 P05177 2/20 1.00
CYP2D6 P10635 2/20 1.00
CYP2C19 P33261 2/20 1.00
CHRM2 P08172 1/20 1.00
ADRA2A P08913 1/20 1.00
CHRM1 P11229 1/20 1.00
SMPD1 P17405 1/20 1.00
DRD1 P21728 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fendiline SCHEMBL5053865 1.00 OPRM1 (1.00) OPRM1CYP3A4LMNAHTR1AADORA3
Fendiline SCHEMBL14415808 1.00 OPRM1 (1.00) OPRM1CYP3A4LMNAHTR1AADORA3
Fendiline SCHEMBL14415809 1.00 OPRM1 (1.00) OPRM1CYP3A4LMNAHTR1AADORA3
Fendiline SCHEMBL15571059 0.98 KMT2A (1.00) OPRM1CYP3A4LMNAHTR1AADORA3
Fendiline SCHEMBL15572599 0.98 KMT2A (1.00) OPRM1CYP3A4LMNAHTR1AADORA3
Fendiline SCHEMBL666530 0.98 KMT2A (1.00) OPRM1CYP3A4LMNAHTR1AADORA3
SCHEMBL9660642 0.93 HTR1A (0.86) OPRM1CYP3A4LMNAHTR1AADORA3
SCHEMBL9662753 0.91 HTR1A (0.83) OPRM1CYP3A4LMNAHTR1AADORA3
SCHEMBL9661837 0.89 HTR1A (0.80) OPRM1CYP3A4LMNAHTR1AADORA3
SCHEMBL9662448 0.89 LMNA (0.80) OPRM1CYP3A4LMNAHTR1AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6213 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741492-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2026-05-13 EP claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
US-12550885-B2 Red blood cell storage solutions, solution additives, and methods for improving the storage of red blood cells UNIVERSITY OF CINCINNATI (US) 2026-02-17 US claimed
EP-4658278-A1 SELECTIVE FIASMA TREATMENT Valo Health, Inc. (US) 2025-12-10 EP claimed
EP-4648769-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2025-11-19 EP claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
CN-118130678-B Liquid chromatography-mass spectrometry detection method for 14 drugs of dizziness, syncope and cerebral apoplexy in blood 中国民用航空局民用航空医学中心 2025-06-10 CN claimed
US-20250152591-A1 TREATMENT OF HEMATOLOGICAL MALIGNANCIES WITH MENIN INHIBITORS AND P-GLYCOPROTEIN INHIBITORS KURA ONCOLOGY INC (US) 2025-05-15 US claimed
WO-2025097070-A1 ORAL DOSAGE FORM WITH CATIONICALLY CHARGEABLE HYDROGEL FOR DELIVERY OF ACTIVE AGENT ENTREGA INC. (US) 2025-05-08 WO claimed
CN-119515952-A Automatic identification method and device for thickness of cable insulating layer 镇江绿建工程咨询有限公司 2025-02-25 CN claimed
WO-1993003711-A1 DOSAGE FORM FOR DELIVERING DRUG IN SHORT-TIME PERIOD ALZA CORPORATION (US) 1993-03-04 WO claimed
US-5190765-A Latent Drug Delivery ALZA CORPORATION (US) 1993-03-02 US claimed
US-5178867-A Dosage form for delivering drug in short-time period ALZA CORPORATION (US) 1993-01-12 US claimed
WO-1993000071-A1 DOSAGE FORM FOR A DELAYED DRUG DELIVERY ALZA CORPORATION (US) 1993-01-07 WO claimed
US-5160744-A Sustained release by coating drug in polyoxyethylene glycol and another polymer that swells and expands and pushes the drug out ALZA CORPORATION (US) 1992-11-03 US claimed
EP-0397848-A1 METHOD OF ATTACHING A COMPOSITE ELASTIC MATERIAL TO AN ARTICLE. KIMBERLY CLARK CO (US) 1990-11-22 EP claimed
US-4851404-A USING CALCIUM PLOCKERS MILES INC. (US) 1989-07-25 US claimed
EP-0078820-B1 INCLUSION COMPLEXES OF N-(1-PHENYLETHYL)-3,3-DIPHENYLPROPYLAMINE RESPECTIVELY THE HYDROCHLORIDE THEREOF WITH CYCLODEXTRIN, A PROCESS FOR THE PREPARATION OF THESE INCLUSION COMPLEXES AS WELL AS PHARMACEUTICAL PREPARATIONS CONTAINING THESE INCLUSION COMPLEXES CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1987-12-09 EP claimed
US-4518588-A CORONARY DILATOR CALCIUM ANTAGONIST CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1985-05-21 US claimed
EP-0008252-B1 ROTATING HYDRAULIC DISTRIBUTOR, PARTICULARLY FOR POWER-ASSISTED STEERING MECHANISMS BENDIBERICA S.A. (ES) 1982-02-24 EP claimed