Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29055932 | 0.87 | ALDH1A1 (0.45) | SMN1; SMN2FAAHPPARGALDH1A1GAA | |
| SCHEMBL29096931 | 0.85 | TOP2A (0.50) | FAAHPPARGALDH1A1GAAKDM4E | |
| SCHEMBL25312191 | 0.84 | ALOX15 (0.44) | PPARGALDH1A1GAAEPHX2 | |
| SCHEMBL29055943 | 0.81 | FAAH (0.43) | SMN1; SMN2FAAHPPARGS1PR4S1PR1 | |
| SCHEMBL19503080 | 0.80 | PPARG (0.55) | PPARGALDH1A1GAAAAK1KDM4E | |
| SCHEMBL25309324 | 0.78 | TOP2A (0.44) | FAAHPPARGS1PR4S1PR1S1PR3 | |
| SCHEMBL12065312 | 0.78 | PPARG (0.46) | PPARGALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL4854202 | 0.78 | FFAR1 (0.47) | PPARGAAK1 | |
| SCHEMBL19503196 | 0.77 | CA12 (0.44) | PPARGALDH1A1GAA | |
| SCHEMBL23118871 | 0.76 | EPHX2 (0.69) | ALDH1A1GAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497316-A2 | GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087070-A2 | GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 2003-10-23 | — | — | WO | disclosed |