SCHEMBL6385161

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL619670	0.90	KDR (0.58)	KDRBRAFRAF1RETEPHX2
	SCHEMBL940461	0.88	KDR (0.62)	KDRBRAFRAF1RETEPHX2
	SCHEMBL4371903	0.86	KDR (0.59)	KDRBRAFRAF1RETEPHX2
	SCHEMBL12355381	0.86	KDR (0.59)	KDRBRAFRAF1RETEPHX2
	SCHEMBL12355380	0.85	KDR (0.50)	KDRBRAFRAF1RETEPHX2
	SCHEMBL6387865	0.85	KDR (0.61)	KDRBRAFRAF1RETEPHX2
	SCHEMBL1219701	0.85	KDR (0.58)	KDRBRAFRAF1RETEPHX2
	SCHEMBL30078261	0.85	KDR (0.61)	KDRBRAFRAF1RETEPHX2
	Ammonia Solution, Strong SCHEMBL1218414	0.85	KDR (0.58)	KDRBRAFRAF1RETEPHX2
	SCHEMBL16651380	0.84	KDR (0.67)	KDRBRAFRAF1RETEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.