Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.55 |
| ▸ | MPL | P40238 | 1/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23610344 | 0.83 | HTR6 (0.49) | HTR6MPLDRD2SMN1; SMN2LMNA | |
| SCHEMBL8472396 | 0.83 | NISCH (0.44) | HTR6TGFBR1DHFRSMN1; SMN2LMNA | |
| SCHEMBL28902429 | 0.81 | MPL (0.55) | HTR6MPLDRD2SMN1; SMN2LMNA | |
| SCHEMBL23610339 | 0.80 | TGFBR1 (0.54) | HTR6MPLTGFBR1DHFRSMN1; SMN2 | |
| SCHEMBL23610349 | 0.80 | TGFBR1 (0.54) | HTR6TGFBR1DHFRLMNAMEN1 | |
| SCHEMBL23618147 | 0.80 | MPL (0.57) | HTR6MPLTGFBR1DHFRSMN1; SMN2 | |
| SCHEMBL6389273 | 0.80 | TGFBR1 (0.53) | HTR6TGFBR1DHFRSMN1; SMN2LMNA | |
| SCHEMBL30256985 | 0.78 | MYC (0.56) | HTR6MPLDRD2SMN1; SMN2LMNA | |
| SCHEMBL28357048 | 0.77 | TGFBR1 (0.57) | TGFBR1DHFRSMN1; SMN2LMNAMEN1 | |
| SCHEMBL23618152 | 0.76 | TGFBR1 (0.50) | HTR6MPLTGFBR1DHFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050154031-A1 | 5-Ht2b receptor antagonists | PHARMAGENE LABORATORIES LIMITED (GB) | 2005-07-14 | — | — | US | disclosed |
| CN-1633293-A | 5-ht2b receptor antagonists | PHARMAGENE LAB LTD (GB) | 2005-06-29 | — | — | CN | disclosed |
| EP-1474141-A1 | 5-HT2B RECEPTOR ANTAGONISTS | Pharmagene Laboratories Ltd (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068227-A1 | 5-HT2B RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050154031-A1 | 5-Ht2b receptor antagonists | HTR2B, HTR3B, HTR7 | HTR6 6/4885MPL 1218/4885TGFBR1 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.