Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.73 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381232 | 0.85 | CYP19A1 (1.00) | CYP19A1ACHEPDE4D | |
| SCHEMBL6384672 | 0.81 | CYP19A1 (0.70) | CYP19A1ACHEPDE4D | |
| SCHEMBL17949493 | 0.80 | ACHE (0.50) | CYP19A1ACHE | |
| SCHEMBL6380946 | 0.80 | CYP19A1 (0.56) | CYP19A1ACHEPDE4D | |
| Hydrochloric Acid SCHEMBL2333536 | 0.80 | ACHE (0.66) | CYP19A1ACHE | |
| SCHEMBL16552713 | 0.79 | ACHE (0.49) | CYP19A1ACHE | |
| Bromide SCHEMBL2406415 | 0.78 | ACHE (0.68) | CYP19A1ACHE | |
| SCHEMBL1114939 | 0.77 | PDE4D (0.81) | CYP19A1ACHEPDE4D | |
| SCHEMBL16552907 | 0.74 | ACHE (0.46) | CYP19A1ACHEPDE4D | |
| SCHEMBL28883602 | 0.74 | CYP19A1 (0.58) | CYP19A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047674-B1 | PROCESS FOR PRODUCTION OF DONEPEZIL DERIVATIVES | EISAI CO LTD (JP) | 2005-03-30 | — | — | EP | disclosed |
| EP-1047674-A1 | PROCESS FOR PRODUCTION OF DONEPEZIL DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999036405-A1 | PROCESS FOR PRODUCTION OF DONEPEZIL DERIVATIVE | EISAI CO., LTD. (JP) | 1999-07-22 | — | — | WO | disclosed |