Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.70 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381232 | 0.83 | CYP19A1 (1.00) | CYP19A1ACHEPDE4D | |
| SCHEMBL6385559 | 0.81 | CYP19A1 (0.73) | CYP19A1ACHEPDE4D | |
| SCHEMBL6380946 | 0.81 | CYP19A1 (0.56) | CYP19A1ACHEPDE4D | |
| SCHEMBL6383533 | 0.80 | PDE4D (0.57) | CYP19A1ACHEPDE4D | |
| Hydrochloric Acid SCHEMBL2331442 | 0.78 | ACHE (0.64) | CYP19A1ACHE | |
| SCHEMBL6384704 | 0.77 | CYP19A1 (0.67) | CYP19A1ACHEPDE4D | |
| Bromide SCHEMBL2334206 | 0.76 | ACHE (0.66) | CYP19A1ACHE | |
| SCHEMBL1114939 | 0.75 | PDE4D (0.81) | CYP19A1ACHEPDE4D | |
| SCHEMBL6825465 | 0.72 | CYP19A1 (1.00) | CYP19A1PDE4D | |
| SCHEMBL11869676 | 0.70 | ACHE (1.00) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047674-B1 | PROCESS FOR PRODUCTION OF DONEPEZIL DERIVATIVES | EISAI CO LTD (JP) | 2005-03-30 | — | — | EP | disclosed |