SCHEMBL638576

SCHEMBL638576

OC1c2cccc3cccc(c23)C1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.45
HSD17B10 Q99714 7/20 0.45
HPGD P15428 5/20 0.45
TSHR P16473 5/20 0.45
CYP1A2 P05177 3/20 0.45
CYP3A4 P08684 3/20 0.45
CYP1A1 P04798 1/20 0.45
CYP1B1 Q16678 1/20 0.45
GAA P10253 6/20 0.39
MEN1 O00255 6/20 0.39
KMT2A Q03164 6/20 0.39
MAPT P10636 4/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
MCL1 Q07820 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
APP P05067 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL638575 1.00 ALDH1A1 (0.45) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL638574 1.00 ALDH1A1 (0.45) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL12486765 0.92 ALDH1A1 (0.50) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL12486766 0.92 ALDH1A1 (0.50) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL2935054 0.92 ALDH1A1 (0.50) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL7638515 0.84 ALDH1A1 (0.36) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL15848326 0.84 ALDH1A1 (0.36) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL7618335 0.84 ALDH1A1 (0.36) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL7638518 0.84 ALDH1A1 (0.36) ALDH1A1HSD17B10HPGDTSHRCYP1A2
SCHEMBL11129011 0.80 ALDH1A1 (0.37) ALDH1A1HSD17B10HPGDTSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600737-B2 Bidentate phosphite ligands, catalytic compositions containing such ligands, and catalytic processes utilizing such catalytic compositions INV NYLON CHEMICALS AMERICAS, LLC (US) 2026-04-14 US claimed
US-20260015370-A1 BIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS, AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS INV NYLON CHEMICALS AMERICAS LLC (US) 2026-01-15 US claimed
US-12600737-B2 Bidentate phosphite ligands, catalytic compositions containing such ligands, and catalytic processes utilizing such catalytic compositions INV NYLON CHEMICALS AMERICAS, LLC (US) 2026-04-14 US disclosed
US-12600737-B2 Bidentate phosphite ligands, catalytic compositions containing such ligands, and catalytic processes utilizing such catalytic compositions INV NYLON CHEMICALS AMERICAS, LLC (US) 2026-04-14 US disclosed
US-20260015370-A1 BIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS, AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS INV NYLON CHEMICALS AMERICAS LLC (US) 2026-01-15 US disclosed
US-20260015370-A1 BIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS, AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS INV NYLON CHEMICALS AMERICAS LLC (US) 2026-01-15 US disclosed
EP-4499654-A1 BIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS, AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS INVISTA Textiles (U.K.) Limited (GB) 2025-02-05 EP disclosed
EP-4499654-A1 BIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS, AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS INVISTA Textiles (U.K.) Limited (GB) 2025-02-05 EP disclosed
US-12084649-B2 Hierarchical magnetic nanoparticle-enzyme mesoporous assemblies embedded in macroporous scaffolds CORNELL UNIVERSITY (US) 2024-09-10 US disclosed
WO-2024028722-A1 BIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS, AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS INV NYLON CHEMICALS AMERICAS, LLC (US) 2024-02-08 WO disclosed
WO-2024028722-A1 BIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS, AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS INV NYLON CHEMICALS AMERICAS, LLC (US) 2024-02-08 WO disclosed
CN-101492331-A Process for producing chiral 2-hydroxyl acenaphthenone compounds UNIV EAST CHINA SCIENCE & TECH (CN) 2009-07-29 CN disclosed
CN-101451152-A Application of baker's yeast in preparation of chiral compounds UNIV EAST CHINA SCIENCE & TECH (CN) 2009-06-10 CN disclosed
CN-101451152-A Application of baker's yeast in preparation of chiral compounds UNIV EAST CHINA SCIENCE & TECH (CN) 2009-06-10 CN disclosed
US-5128429-A Low temperature block polymerization without randomization RAYCHEM LIMITED (GB) 1992-07-07 US disclosed
EP-0154506-B1 PREPARATION OF ORGANIC POLYMERS RAYCHEM LIMITED (GB) 1992-02-05 EP disclosed
US-4999411-A Polythioethers, polythiocarbonates, polythioamides, polythioimides RAYCHEM LIMITED (GB) 1991-03-12 US disclosed
US-4960835-A ENGINEERING THERMOPLASTICS RAYCHEM LIMITED (GB) 1990-10-02 US disclosed
US-4845179-A CONDENSATION POLYMERIZATION RAYCHEM LIMITED (GB) 1989-07-04 US disclosed
EP-0154506-A2 Preparation of organic polymers RAYCHEM LIMITED (GB) 1985-09-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015370-A1 BIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS, AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS HPD, CYC1, BMP1 ALDH1A1 1127/4885HSD17B10 1039/4885HPGD 179/4885
US-12600737-B2 Bidentate phosphite ligands, catalytic compositions containing such ligands, and catalytic processes utilizing such catalytic compositions BMP1, BPNT1, HPD ALDH1A1 997/4885HSD17B10 1655/4885HPGD 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.