Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 12/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 9/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11383181 | 0.85 | CDC25B (0.56) | CDC25BCNR2NR4A1NR4A2NR4A3 | |
| SCHEMBL3282521 | 0.83 | WDR5 (0.47) | CDC25BCNR2NR4A1NR4A2NR4A3 | |
| SCHEMBL5911605 | 0.83 | MEN1 (0.49) | CDC25BCNR2NR4A1NR4A2NR4A3 | |
| SCHEMBL29414437 | 0.82 | CDC25B (0.80) | CDC25BCNR2NR4A1NR4A2NR4A3 | |
| SCHEMBL244802 | 0.82 | CDC25B (0.80) | CDC25BCNR2NR4A1NR4A2NR4A3 | |
| SCHEMBL6539256 | 0.81 | WDR5 (0.61) | CDC25BNR4A1NR4A2NR4A3MEN1 | |
| Hydrochloric Acid SCHEMBL27713225 | 0.80 | CDC25B (0.77) | CDC25BCNR2NR4A1NR4A2NR4A3 | |
| SCHEMBL3246521 | 0.79 | ALDH1A1 (0.46) | NR4A1NR4A2NR4A3MEN1MAPT | |
| SCHEMBL5911604 | 0.79 | CDC25B (0.61) | CDC25BCNR2NR4A1NR4A2NR4A3 | |
| SCHEMBL8710831 | 0.78 | MEN1 (0.50) | MEN1MAPTHTTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9453015-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-20150166536-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-06-18 | — | — | US | disclosed |
| US-8980888-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20140378447-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2014-12-25 | — | — | US | disclosed |
| EP-2528914-A1 | FURO [3, 2 -B]PYRANE DERIVATIVES USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS | Eisai R&D Management Co., Ltd. (JP) | 2012-12-05 | — | — | EP | disclosed |
| WO-2011094339-A1 | FURO [3, 2 -B] PYRANE DERIVATIVES USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |
| US-20090137580-A1 | Fused Heterocyclic Derivatives and Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166536-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | CDC25B 3214/4885CNR2 2311/4885NR4A1 2558/4885 |
| US-20140378447-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | CDC25B 3214/4885CNR2 2311/4885NR4A1 2558/4885 |
| US-20090137580-A1 | Fused Heterocyclic Derivatives and Use Thereof | TIE1, KDR, FLT1 | CDC25B 255/4885CNR2 69/4885NR4A1 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.