Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.61 |
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282521 | 0.84 | WDR5 (0.47) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL7191625 | 0.84 | WDR5 (0.59) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL3246521 | 0.84 | ALDH1A1 (0.46) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL63859 | 0.81 | CDC25B (0.57) | WDR5NR4A1NR4A2NR4A3CDC25B | |
| SCHEMBL6948196 | 0.80 | WDR5 (0.42) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL6539923 | 0.80 | MAPT (0.49) | WDR5NR4A2ALDH1A1HPGDLMNA | |
| SCHEMBL4938311 | 0.78 | CYP1A1 (0.46) | WDR5LDHAALDH1A1HPGDLMNA | |
| SCHEMBL5911605 | 0.78 | MEN1 (0.49) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL10898764 | 0.77 | PTPN1 (0.56) | WDR5ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL29721418 | 0.76 | WDR5 (1.00) | WDR5LDHANR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812235-B2 | 2-ACYLAMINO- BETA -ALANINE DERIVATIVES AND A PHARMACEUTICALLY ACCEPTABLE SALT, USEFUL AS FIBRINOGEN RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-02 | — | — | US | disclosed |
| US-20030018193-A1 | Beta-alanine derivatives and their use as receptor anatgonists | ASTELLAS PHARMA INC. (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-1255748-A1 | BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001060813-A1 | BETA-ALANINE DERIVATIVES AND THEIR USE AS RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |
| WO-2000011017-A9 | CARDENOLIDE COMPLEXES USEFUL AS CARDIOACTIVE AGENTS | UNIV COLUMBIA (US) | 2000-06-22 | — | — | WO | disclosed |
| WO-2000011017-A2 | CARDENOLIDE COMPLEXES USEFUL AS CARDIOACTIVE AGENTS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2000-03-02 | — | — | WO | disclosed |
| US-3936478-A | Process for the preparation of desmosterol derivatives | TEIJIN LIMITED (JA) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018193-A1 | Beta-alanine derivatives and their use as receptor anatgonists | ARRB1, ADRB1, GLRB | WDR5 4659/4885LDHA 333/4885NR4A1 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.