Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6388818 | 0.92 | RAD52 (0.35) | RAD52GAATHRBKDM4EMAPT | |
| SCHEMBL6384690 | 0.87 | RAD52 (0.36) | RAD52GAATHRBKDM4EMAPT | |
| SCHEMBL6386455 | 0.83 | POLB (0.37) | RAD52GAATHRB | |
| SCHEMBL6390344 | 0.83 | THRB (0.36) | RAD52GAATHRB | |
| SCHEMBL6387832 | 0.82 | GBA1 (0.33) | — | |
| SCHEMBL6387450 | 0.76 | RAD52 (0.39) | RAD52GAATHRBKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL6095935 | 0.76 | RAD52 (0.40) | RAD52GAATHRBKDM4EMAPT | |
| SCHEMBL6385931 | 0.75 | RAD52 (0.35) | RAD52GAATHRBKDM4EMAPT | |
| SCHEMBL6385952 | 0.75 | RAD52 (0.35) | RAD52GAATHRBKDM4EMAPT | |
| SCHEMBL6386855 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050097682-A9 | Oxidation dyeing composition based on 1-(4-aminophenyl)pyrrolidines substituted in positions 2 and 4 | L'OREAL S.A. (FR) | 2005-05-12 | — | — | US | claimed |
| US-20050097682-A9 | Oxidation dyeing composition based on 1-(4-aminophenyl)pyrrolidines substituted in positions 2 and 4 | L'OREAL S.A. (FR) | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050097682-A9 | Oxidation dyeing composition based on 1-(4-aminophenyl)pyrrolidines substituted in positions 2 and 4 | PYCR1, KRT18, COX5A | RAD52 563/4885GAA 4471/4885THRB 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.