Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864811 | 0.83 | — | — | |
| SCHEMBL8065587 | 0.82 | — | — | |
| SCHEMBL6276533 | 0.64 | LMNA (0.36) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL30724578 | 0.63 | LMNA (0.35) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16501134 | 0.61 | LMNA (0.38) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL24378167 | 0.60 | LMNA (0.36) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1993537 | 0.60 | LMNA (0.36) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31560438 | 0.60 | LMNA (0.36) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL30425332 | 0.60 | LMNA (0.36) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL30015637 | 0.60 | LMNA (0.36) | LMNAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884804-B2 | Inhibitors of Src and other protein kinases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2005-04-26 | — | — | US | claimed |