Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HMGCR | P04035 | 4/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6389327 | 1.00 | TSHR (0.48) | TSHRHMGCRPTPN7RECQLTDP1 | |
| SCHEMBL9626686 | 0.86 | HMGCR (0.58) | HMGCRPTPN7 | |
| SCHEMBL12003762 | 0.86 | HMGCR (0.45) | TSHRHMGCRPTPN7DNM1 | |
| SCHEMBL6361700 | 0.85 | HMGCR (0.46) | TSHRHMGCRPTPN7 | |
| SCHEMBL6137599 | 0.85 | HMGCR (0.46) | TSHRHMGCRPTPN7 | |
| SCHEMBL6137606 | 0.85 | HMGCR (0.46) | TSHRHMGCRPTPN7 | |
| SCHEMBL6137410 | 0.83 | HMGCR (0.45) | HMGCRPTPN7RECQLTDP1DNM1 | |
| SCHEMBL6137458 | 0.83 | HMGCR (0.45) | HMGCRPTPN7RECQLTDP1DNM1 | |
| SCHEMBL6137452 | 0.83 | HMGCR (0.45) | HMGCRPTPN7RECQLTDP1DNM1 | |
| SCHEMBL6137271 | 0.83 | HMGCR (0.45) | HMGCRPTPN7RECQLTDP1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038259-A1 | Hydroxyeicosenoic acid anaglogs | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038259-A1 | Hydroxyeicosenoic acid anaglogs | HCAR1, HRH4, HCAR3 | TSHR 907/4885HMGCR 226/4885PTPN7 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.