Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 19/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491452 | 0.82 | CYP1A2 (0.34) | KIF11 | |
| SCHEMBL5997583 | 0.82 | KIF11 (0.41) | KIF11DNMT1 | |
| SCHEMBL6389455 | 0.76 | MDM4 (0.51) | — | |
| SCHEMBL6389469 | 0.76 | MDM4 (0.51) | — | |
| SCHEMBL418100 | 0.74 | CYP1A2 (0.38) | — | |
| Trifluoroacetic Acid SCHEMBL4363452 | 0.73 | CTRB1 (0.36) | — | |
| SCHEMBL4599750 | 0.73 | CYP1A2 (0.38) | — | |
| SCHEMBL1405820 | 0.73 | CYP1A2 (0.38) | — | |
| SCHEMBL1405873 | 0.73 | CYP1A2 (0.38) | — | |
| SCHEMBL30510259 | 0.73 | CYP1A2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529037-A2 | SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | Genzyme Corporation (US) | 2005-05-11 | — | — | EP | disclosed |
| WO-2003097622-A2 | SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | GENZYME CORPORATION (US) | 2003-11-27 | — | — | WO | disclosed |