Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | HINT1 | P49773 | 7/20 | 0.56 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | PNP | P00491 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275031 | 0.84 | HINT1 (0.58) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL29060313 | 0.81 | HINT1 (0.69) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL780400 | 0.81 | TAAR1 (0.58) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL23200376 | 0.81 | TAAR1 (0.58) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL800400 | 0.81 | TAAR1 (0.58) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL23200375 | 0.81 | TAAR1 (0.58) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL23710671 | 0.81 | TAAR1 (0.58) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL23710670 | 0.81 | TAAR1 (0.58) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL800874 | 0.81 | TAAR1 (0.58) | TAAR1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL1527362 | 0.81 | NT5E (0.59) | TAAR1HINT1GSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525209-A2 | 1'-, 2'- AND 3' -MODIFIED NUCLEOSIDE DERIVATIVES FOR TREATING FLAVIVIRIDAE INFECTIONS | Idenix (Cayman) Limited (KY) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004003000-A2 | 1’-, 2'- AND 3'- MODIFIED NUCLEOSIDE DERIVATIVES FOR TREATING FLAVIVIRIDAE INFECTIONS | IDENIX (CAYMAN) LIMITED (KY) | 2004-01-08 | — | — | WO | disclosed |