Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 3/20 | 0.45 |
| ▸ | MAX | P61244 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244028 | 0.96 | MYC (0.51) | ALDH1A1KMT2AMEN1HPGDLMNA | |
| SCHEMBL5284618 | 0.85 | RORA (0.60) | ALDH1A1KMT2AMEN1HPGDLMNA | |
| SCHEMBL6397094 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1HPGDLMNA | |
| SCHEMBL5244533 | 0.82 | KMT2A (0.62) | ALDH1A1KMT2AMEN1HPGDLMNA | |
| SCHEMBL8160125 | 0.80 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL16141954 | 0.79 | MYC (0.57) | ALDH1A1KMT2AMEN1NPC1MYC | |
| SCHEMBL6392618 | 0.78 | KMT2A (0.58) | ALDH1A1KMT2AMEN1HPGDLMNA | |
| SCHEMBL5242897 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1HPGDLMNA | |
| SCHEMBL5246275 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1HPGDLMNA | |
| SCHEMBL5245942 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006002284-A1 | UBIQUITIN LIGASE INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| US-20050282818-A1 | Ubiquitin ligase inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282818-A1 | Ubiquitin ligase inhibitors | NEDD4, TRAF6, XIAP | ALDH1A1 2627/4885KMT2A 1303/4885MEN1 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.