SCHEMBL6394341

SCHEMBL6394341

CCC(CC)C[C@@H](C)OC(=O)c1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.54
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
CA7 P43166 3/20 0.54
CA9 Q16790 3/20 0.54
CA14 Q9ULX7 3/20 0.54
ALDH1A1 P00352 2/20 0.50
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
ESR1 P03372 4/20 0.46
ESR2 Q92731 2/20 0.46
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.44
TSHR P16473 3/20 0.44
CHRM1 P11229 1/20 0.44
SLC6A2 P23975 1/20 0.44
KDR P35968 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HSD17B1 P14061 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6388164 0.95 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL6388169 0.95 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL9437187 0.88 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL9437191 0.88 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL6547272 0.86 PDCD1 (0.44) ALDH1A1PDCD1CD274TSHRSMN1; SMN2
SCHEMBL6562073 0.85 CYP4F2 (0.48) ALDH1A1PDCD1CD274KDM4ETSHR
SCHEMBL6547348 0.85 PDCD1 (0.57) PDCD1CD274KDM4ESMN1; SMN2ADRB1
SCHEMBL6387977 0.83 HSD17B10 (0.50) PDCD1CD274LMNATSHRTDP1
SCHEMBL9724886 0.82 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL39298 0.82 CA12 (0.67) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050260358-A1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-11-24 US disclosed
US-6730371-B2 LIQUID CRYSTAL DISPLAY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-05-04 US disclosed
EP-1225212-B1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL CO (JP) 2004-03-24 EP disclosed
EP-1249484-B1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL CO (JP) 2004-01-28 EP disclosed
EP-1380567-A1 Chiral compounds as dopants for liquid crystals MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-01-14 EP disclosed
US-6677475-B2 FOR USE IN LIQUID CRYSTAL DISPLAY DEVICE MITSUBISHI GAS CHEMICAL CO., INC. (JP) 2004-01-13 US disclosed
US-20030054119-A1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL CO., INC. 2003-03-20 US disclosed
EP-1249484-A1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-10-16 EP disclosed
US-20020146517-A1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. 2002-10-10 US disclosed
EP-1225212-A1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-07-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030054119-A1 Optically active compound and liquid crystal composition containing the compound HDHD5, THOC2, TDO2 CA12 2113/4885CA1 1913/4885CA2 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.