SCHEMBL6394396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4919198	0.93	TACR1 (0.52)	TACR1SLC6A2SLC6A4SLC6A3CYP2D6
	SCHEMBL340465	0.83	SLC6A2 (0.51)	TACR1SLC6A2SLC6A4SLC6A3CYP2D6
	SCHEMBL4912849	0.81	ALOX5 (0.52)	TACR1SLC6A2SLC6A4SLC6A3KCNH2
	SCHEMBL339372	0.76	TACR1 (0.57)	TACR1SLC6A2SLC6A4SLC6A3CYP2D6
	SCHEMBL4210498	0.75	MBTPS1 (0.59)	SLC6A2SLC6A4SLC6A3KCNH2MBTPS1
	SCHEMBL339220	0.73	TACR1 (0.61)	TACR1SLC6A2SLC6A4SLC6A3KCNH2
	SCHEMBL341939	0.72	ALOX5 (0.60)	SLC6A2SLC6A4SLC6A3KCNH2OPRM1
	SCHEMBL339704	0.71	TACR1 (0.55)	TACR1SLC6A2SLC6A4SLC6A3KCNH2
	SCHEMBL340969	0.71	ALOX5 (0.55)	SLC6A2SLC6A4SLC6A3KCNH2RPLP1
	SCHEMBL28770699	0.71	TACR1 (0.57)	TACR1SLC6A2SLC6A4SLC6A3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.