Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396268 | 0.74 | POLB (0.43) | POLBSMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL4744925 | 0.70 | POLB (0.42) | POLBSMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL5142027 | 0.68 | TSHR (0.42) | POLBSMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL4754122 | 0.68 | TSHR (0.56) | POLBALDH1A1TSHRLMNAMAPT | |
| SCHEMBL9393377 | 0.67 | KCNQ2 (0.44) | SMN1; SMN2ALDH1A1TSHRHTTCYP3A4 | |
| SCHEMBL27607927 | 0.66 | POLB (0.39) | POLBSMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL8939923 | 0.65 | ALDH1A1 (0.47) | POLBSMN1; SMN2PKMALDH1A1TSHR | |
| SCHEMBL8939927 | 0.65 | HTT (0.38) | POLBSMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL6396274 | 0.64 | SMN1; SMN2 (0.47) | POLBSMN1; SMN2PKMALDH1A1TSHR | |
| SCHEMBL18505994 | 0.64 | SMN1; SMN2 (0.47) | POLBSMN1; SMN2ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155141-A2 | NOVEL FACULTATIVE CATONIC STEROLS | NOVOSOM AG (DE) | 2008-12-24 | — | — | WO | disclosed |