Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5993310 | 0.87 | NPC1 (0.48) | NPC1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL152305 | 0.78 | TDP1 (0.37) | NPC1RAB9AALDH1A1GAAHPGD | |
| SCHEMBL5994596 | 0.76 | CYP3A4 (0.41) | MAPTKMT2AMEN1ABCG2HPGD | |
| SCHEMBL6399268 | 0.74 | CYP3A4 (0.40) | MAPTKMT2AMEN1ABCG2HPGD | |
| SCHEMBL5997923 | 0.74 | L3MBTL1 (0.36) | KMT2AMEN1ALDH1A1GAAHPGD | |
| SCHEMBL855232 | 0.74 | NPC1 (0.60) | NPC1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL5994244 | 0.72 | ALDH1A1 (0.46) | NPC1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL6396397 | 0.71 | TP53 (0.43) | NPC1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL2540822 | 0.71 | NPC1 (0.50) | NPC1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL5994813 | 0.71 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969733-B2 | Photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-11-29 | — | — | US | disclosed |
| US-20030139485-A1 | Photoinitiators | WOLF JEAN-PIERRE (CH) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139485-A1 | Photoinitiators | DHCR24, NR1I3, CBR1 | NPC1 850/4885MAPT 4713/4885KMT2A 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.