Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | CPB1 | P15086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6392871 | 0.94 | AKT1 (0.31) | ADORA2BAKT1HCAR2CPB1 | |
| SCHEMBL186274 | 0.72 | NOS1 (0.52) | — | |
| SCHEMBL4590823 | 0.71 | HCAR2 (0.31) | HCAR2 | |
| SCHEMBL18825946 | 0.71 | KDR (0.41) | ADORA2BAKT1KDRHCAR2 | |
| SCHEMBL3559920 | 0.71 | CYP2C19 (0.38) | — | |
| SCHEMBL8542775 | 0.71 | NOS1 (0.50) | — | |
| SCHEMBL3173918 | 0.71 | NOS1 (0.50) | — | |
| SCHEMBL31087550 | 0.70 | KDR (0.43) | ADORA2BKDRHCAR2 | |
| SCHEMBL146605 | 0.70 | KDR (0.43) | ADORA2BKDRHCAR2 | |
| SCHEMBL3153900 | 0.69 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026929-A1 | Novel phenyl derivatives as inducers of apoptosis | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026929-A1 | Novel phenyl derivatives as inducers of apoptosis | BAX, BAD, CASP3 | ADORA2B 4165/4885AKT1 2041/4885KDR 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.